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IL4
interleukin 4
IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
| Gene Name: | interleukin 4 |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | IL4, B cell growth factor 1, B-cell stimulatory factor 1, B_cell stimulatory factor 1, BCGF1, BSF-1, Binetrakin, BCGF-1, Interleukin 4, Interleukin-4, Pitrakinra, BSF1, IL-4 |
| Target Sequences: | NM_000589 NP_000580.1 P05112 |
Publications (3)
1
Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Gong G, Shao L, Wang Y, Chen CY, Huang D, Yao S, Zhan X, Sicard H, Wang R, Chen ZW. Blood. 2009 113:837-45.
[PubMed:18981295]
[PMC:PMC2630269]
Related Antibodies: LS-C41019.
2
Modulation of Binge-like Ethanol Consumption by IL-10 Signaling in the Basolateral Amygdala. S Alex Marshall, Kyle H McKnight, Allyson K Blose, Donald T Lysle, Todd E Thiele. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2017 June;12:249-259. [Full Text Article]
[PubMed:27640210]
[PMC:PMC5357210]
Related Antibodies: LS-C745952.
3
Delivery of Interleukin-4-Encoding Lentivirus Using Multiple-Channel Bridges Enhances Nerve Regeneration. S Ahmed Ali, John E Hanks, Aaron W Stebbins, Osama Alkhalili, Samantha T Cohen, Jessica Y Chen, Dominique R Smith, Courtney M Dumont, Lonnie D Shea, Norman D Hogikyan, Eva L Feldman, Michael J Brenner. The Laryngoscope. 2020 December;130:2802-2810. [Full Text Article]
[PubMed:32220076]
[PMC:PMC7893531]
Related Antibodies: LS-C408858.
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Publications
No
(251)
Yes
(3)
IL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
IL4 Rabbit anti-Human Polyclonal (aa122-150) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL4 Rat anti-Human Monoclonal (PerCP) (MP4-25D2) Antibody
Human
ELISA, Flo, IHC
PerCP Conjugated
25 µg/$236; 100 µg/$251
IL4 Mouse anti-Human Monoclonal (860A 4B3) Antibody
Human
ELISA, SwELISA
Unconjugated
500 µg/$780
IL4 Mouse anti-Human Monoclonal (8D4-8) Antibody
Human, Monkey
ELISA, Flo, IHC, IP
Unconjugated
50 µg/$264
IL4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL4 Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
Flo
PE Conjugated
500 µl/$1,009
IL4 Mouse anti-Bovine Monoclonal (PE) Antibody
Goat, Dog, Sheep, Bovine, Pig, Mustelid
Flo
PE Conjugated
100 Tests/$984
IL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
IL4 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, IHC, IP, WB
Unconjugated
500 µg/$763; 1 mg/$957
IL4 Goat anti-Rabbit Polyclonal Antibody
Rabbit
ELISA, WB
Unconjugated
0.1 mg/$596
IL4 Mouse anti-Bovine Monoclonal (CC313) Antibody
Bovine
ELISA
Unconjugated
0.5 mg/$571
IL4 Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo, IF, WB
Unconjugated
500 µg/$548
IL4 Mouse anti-Bovine Monoclonal (FITC) (CC303) Antibody
Bovine
Flo
FITC Conjugated
0.1 mg/$652
IL4 Rat anti-Mouse Monoclonal (BVD4-1D11) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
0.5 mg/$534
IL4 Rabbit anti-Human Polyclonal (aa122-150) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
IL4 Rabbit anti-Human Polyclonal (aa25-153) Antibody
Human
ELISA, IHC, IHC-P, IP, Neut, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL4 Rabbit anti-Human Polyclonal (aa72-88) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL4 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Neut, WB
Unconjugated
50 µg/$494
IL4 Mouse anti-Bovine Monoclonal (CC303) Antibody
Bovine
ELISA, Flo
Unconjugated
0.5 mg/$714
IL4 Rat anti-Mouse Monoclonal (11B11) Antibody
Mouse
ELISA, ELISPOT
Unconjugated
50 µg/$270; 500 µg/$402
IL4 Rabbit anti-Dog Polyclonal Antibody
Dog
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25
of 254
product results
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