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IL4

interleukin 4

IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene Name: interleukin 4
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL4, B cell growth factor 1, B-cell stimulatory factor 1, B_cell stimulatory factor 1, BCGF1, BSF-1, Binetrakin, BCGF-1, Interleukin 4, Interleukin-4, Pitrakinra, BSF1, IL-4
Target Sequences: NM_000589 NP_000580.1 P05112

Publications (3)

1
Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Gong G, Shao L, Wang Y, Chen CY, Huang D, Yao S, Zhan X, Sicard H, Wang R, Chen ZW. Blood. 2009 113:837-45. [PubMed:18981295] [PMC:PMC2630269] Related Antibodies: LS-C41019.
2
Modulation of Binge-like Ethanol Consumption by IL-10 Signaling in the Basolateral Amygdala. S Alex Marshall, Kyle H McKnight, Allyson K Blose, Donald T Lysle, Todd E Thiele. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2017 June;12:249-259. [Full Text Article] [PubMed:27640210] [PMC:PMC5357210] Related Antibodies: LS-C745952.
3
Delivery of Interleukin-4-Encoding Lentivirus Using Multiple-Channel Bridges Enhances Nerve Regeneration. S Ahmed Ali, John E Hanks, Aaron W Stebbins, Osama Alkhalili, Samantha T Cohen, Jessica Y Chen, Dominique R Smith, Courtney M Dumont, Lonnie D Shea, Norman D Hogikyan, Eva L Feldman, Michael J Brenner. The Laryngoscope. 2020 December;130:2802-2810. [Full Text Article] [PubMed:32220076] [PMC:PMC7893531] Related Antibodies: LS-C408858.

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IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
IL4 ELISA Kit
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Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
3.13 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Biological Fluids, Plasma, Serum, Tissue Homogenates
1 Plate/$783
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
IL4 ELISA Kit
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Sandwich
96-Well Microplate
Pig
1.6 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$700
IL4 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.819 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$470
IL4 ELISA Kit
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Development Kit
1000 Wells
Mouse
16 - 2000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
IL4 ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$610
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$940
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Canine
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
IL4 ELISA Kit
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Sandwich
96-Well Strip Plate
Goat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL4 ELISA Kit
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Development Kit
200 Wells
Mouse
12 - 3000 pg/ml
Colorimetric - 450nm (TMB)
1 Test/$180
IL4 ELISA Kit
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Development Kit
Antibody Pair and Standard
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,005; 1000 Wells/$1,451
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).