Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

IL37

interleukin 37

IL37 is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: interleukin 37
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL37, FIL1, FIL1 zeta, FIL1(ZETA), IL-1 zeta, IL-1F7, IL-1H, IL-1RP1, IL-1X, IL-37, Interleukin-1 homolog 4, Interleukin-1 zeta, Interleukin-1-related protein, Interleukin-23, Interleukin-37, IL1F7, Interleukin 1, zeta, Interleukin-1 family member 7, FIL1Z, IL-1H4, IL1RP1, Interleukin 1 family member 7, Interleukin 37, IL-1X protein, IL1H4, Interleukin-1 superfamily z
Target Sequences: NM_014439 NP_055254.2 Q9NZH6

Publications (2)

1
miR-31 is a broad regulator of ß1-integrin expression and function in cancer cells. Augoff K, Das M, Bialkowska K, McCue B, Plow EF, Sossey-Alaoui K. Molecular cancer research : MCR. 2011 9:1500-8. (IHC; Human) [Full Text Article] [PubMed:21875932] [PMC:PMC3219821]
2
Tuberculosis-sensitized monocytes sustain immune response of interleukin-37. Zhang JA, Liu GB, Zheng BY, Lu YB, Gao YC, Cai XZ, Dai YC, Yu SY, Jia Y, Chen C, Zhuang ZG, Wang X, Wang WD, Fu XX, Yi LL, Shen L, Chen ZW, Xu JF. Molecular immunology. 2016 November;79:14-21. (Human) [Full Text Article] [PubMed:27689749] [PMC:PMC5760171] Related Antibodies: LS-C133726.

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (4)
Recombinant (11)
IL37 (15)
Product Group
Coronavirus Antibodies Proteins cDNAs (15)
Cytokine Release Syndrome Proteins (15)
No (15)
GST (1)
His (1)
His,C-terminus (2)
His-T7 (2)
Myc-DDK (Flag) (5)
Human (13)
293T Cells (2)
E. coli (9)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (5)
Biologically active (2)
Select
E. coli
None
Biologically active
19.4 kDa
5 µg/$268; 25 µg/$349
Select
E. coli
None
Biologically active
19.4 kDa
5 µg/$282; 25 µg/$370
Select
E. coli
His,C-terminus
Less than 0.1 EU/µg protein (determined by LAL method).
~20 kDa (SDS-PAGE)
10 µg/$372; 50 µg/$748
IL37 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.3 kDa
100 µg/$494
IL37 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$150
IL37 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.3 kDa
20 µg/$150
IL37 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
100 µg/$494
IL37 Protein - 12.5% SDS-PAGE of human IL1F7 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
49.72 kDa
10 µg/$479; 25 µg/$670
IL37 Protein - Purified recombinant protein IL37 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$1,107
IL37 Protein - N.A.
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~19.5 kDa
10 µg/$357; 100 µg/$1,530; 1 mg/$4,099
IL37 Protein - NH2-terminal sequence analysis.
Select
E. coli
His
Less than 0.1 EU/µg protein (determined by LAL method).
~20kDa (SDS-PAGE)
50 µg/$828; 10 µg/$421
Select
E. coli
His,C-terminus
Less than 0.01 EU/µg protein (determined by LAL method).
~30 kDa (SDS-PAGE)
10 µg/$351
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
18.7kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
IL37 Protein - Recombinant Interleukin 1 Zeta By SDS-PAGE
Select
E. coli
His-T7
22.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
IL37 Protein - Recombinant Interleukin 1 Zeta By SDS-PAGE
Select
E. coli
His-T7
23.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Viewing 1-15 of 15 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).