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IL37

interleukin 37

IL37 is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: interleukin 37
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL37, FIL1, FIL1 zeta, FIL1(ZETA), IL-1 zeta, IL-1F7, IL-1H, IL-1RP1, IL-1X, IL-37, Interleukin-1 homolog 4, Interleukin-1 zeta, Interleukin-1-related protein, Interleukin-23, Interleukin-37, IL1F7, Interleukin 1, zeta, Interleukin-1 family member 7, FIL1Z, IL-1H4, IL1RP1, Interleukin 1 family member 7, Interleukin 37, IL-1X protein, IL1H4, Interleukin-1 superfamily z
Target Sequences: NM_014439 NP_055254.2 Q9NZH6

Publications (2)

1
miR-31 is a broad regulator of ß1-integrin expression and function in cancer cells. Augoff K, Das M, Bialkowska K, McCue B, Plow EF, Sossey-Alaoui K. Molecular cancer research : MCR. 2011 9:1500-8. (IHC; Human) [Full Text Article] [PubMed:21875932] [PMC:PMC3219821]
2
Tuberculosis-sensitized monocytes sustain immune response of interleukin-37. Zhang JA, Liu GB, Zheng BY, Lu YB, Gao YC, Cai XZ, Dai YC, Yu SY, Jia Y, Chen C, Zhuang ZG, Wang X, Wang WD, Fu XX, Yi LL, Shen L, Chen ZW, Xu JF. Molecular immunology. 2016 November;79:14-21. (Human) [Full Text Article] [PubMed:27689749] [PMC:PMC5760171] Related Antibodies: LS-C133726.

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IL37 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$600
IL37 ELISA Kit
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96-Well Strip Plate
Human
1.37 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$968
IL37 ELISA Kit
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96-Well Microplate
Human
81.92 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
IL37 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$958
IL37 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IL37 ELISA Kit
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Sandwich
96-Well Microplate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IL37 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL37 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
IL37 ELISA Kit
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Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$718
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).