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IL36RN / IL1F5

interleukin 36 receptor antagonist

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Gene Name: interleukin 36 receptor antagonist
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL36RN, FIL1, FIL1D, IL-1 delta, IL-1 related protein 3, IL-1HY1, IL-1RP3, IL-1-related protein 3, IL1F5, IL1RP3, IL1L1, IL36RA, Interleukin-1 delta, Family of interleukin 1-delta, FIL1 delta, IL-1L1, IL-1ra homolog 1, Interleukin-1 family member 5, Interleukin-1-like protein 1, FIL1(DELTA), IL-1F5, IL1HY1, Interleukin-1 HY1, PSORP
Target Sequences: NM_012275 NP_036407.1 Q9UBH0

☰ Filters
Products
Antibodies (64)
Primary (64)
IL36RN / IL1F5 (64)
Human (47)
Mouse (23)
Rat (8)
Bovine (4)
Dog (3)
Gibbon (6)
Monkey (3)
IHC (8)
IHC-P (3)
WB (54)
ELISA (28)
IF (1)
Peptide-ELISA (1)
rabbit (62)
mouse (2)
Product Group
IHCPlus (1)
IgG (23)
IgG1 (1)
monoclonal mc (2)
polyclonal pc (62)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (8)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
Liquid (1)
Lyophilized (1)
PE Conjugated (4)
Preservative Free (2)
Unconjugated (28)
aa12-151 (16)
C-Terminus (8)
aa1-156 (8)
aa76-104 (6)
aa1-155 (5)
Internal (1)
No (64)
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa76-104) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa76-104) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa76-104) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa76-104) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa76-104) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa76-104) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
IL36RN / IL1F5 Antibody - Immunohistochemistry of paraffin-embedded human skin tissue using antibody at 1:100 dilution.
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa1-155) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
IL36RN / IL1F5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$361
Select
IL36RN / IL1F5 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ELISA, IHC-P
Unconjugated, Preservative Free
100 µl/$412
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$386
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL36RN / IL1F5 Antibody - Western blot All lanes: IL36RN antibody at 16µg/ml + Mouse stomach tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa
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IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa1-155) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa1-155) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa1-155) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
IL36RN / IL1F5 Rabbit anti-Human Polyclonal (aa1-155) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
IL36RN / IL1F5 Rabbit anti-Bovine Polyclonal Antibody
Bovine
ELISA, WB
Unconjugated
0.1 mg/$596
IL36RN / IL1F5 Antibody - Anti-Bovine IL-1F5 Antibody - Western Blot. Western blot of Protein-A Purified anti-bovine IL-1F5 antibody shows detection of recombinant bovine IL-1F5 at 17.1 kD (arrowhead) raised in yeast. The identity of the band at 36 kD is not known. The protein was purified and resolved by SDS-PAGE, then transferred to PVDF membrane. Membrane was blocked with 3% BSA (BSA-30, diluted 1:10), and probed with 1 ug/mL primary antibody overnight at 4C. After washing, membrane was probed with IRDye800 Conjugated Goat Anti-Rabbit IgG ( for 45 min at room temperature.
Select
IL36RN / IL1F5 Rabbit anti-Bovine Polyclonal (Lyophilized) Antibody
Bovine
ELISA, WB
Unconjugated, Lyophilized
100 µg/$567
IL36RN / IL1F5 Antibody - Western blot using the Protein-A Purified anti-bovine IL-1F5 antibody shows detection of recombinant bovine IL-1F5 at 17.1 kDa (arrowhead) raised in yeast. The identity of the band at 36 kDa is not known. The protein was purified and resolved by SDS-PAGE, then transferred to PVDF membrane. Membrane was blocked with 3% BSA (BSA-30, diluted 1:10), and probed with 1 µg/mL primary antibody overnight at 4°C. After washing, membrane was probed with for 45 min at room temperature.
Select
IL36RN / IL1F5 Rabbit anti-Bovine Polyclonal (Liquid) Antibody
Bovine
ELISA, WB
Unconjugated, Liquid
25 µl/$304
IL36RN / IL1F5 Antibody - Western blot analysis of IL1F5 expression in Transfected 293T cells lysate. The lane on the left is treated with the antigen-specific peptide.
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IL36RN / IL1F5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
IL36RN / IL1F5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
IL36RN / IL1F5 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
IL36RN / IL1F5 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
Select
IL36RN / IL1F5 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
IL36RN / IL1F5 Antibody - Western blot of recombinant IL36RN / IL1F5.
Select
IL36RN / IL1F5 Rabbit anti-Mouse Polyclonal (aa1-156) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).