order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
IL24
interleukin 24
IL24 is a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
| Gene Name: | interleukin 24 |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL24, FISP, IL10B, IL-24, IL-4-induced secreted protein, Interleukin 24, Interleukin-24, Melanocyte-associated Mda-7, Mob-5, ST16, Mda-7, MDA7, MOB5, C49A |
| Target Sequences: | NM_006850 NP_006841.1 Q13007 |
Publications (1)
Your search did not match any products.
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
