IL22RA1 / IL22R

interleukin 22 receptor, alpha 1

A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-a 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

IL22RA1 / IL22R (8)

Publications

No (8)

Tag

6His, N-terminus (1)

Fc (1)

GST (1)

GST, N-terminus (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Rat (2)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Rat IL22RA1 / IL22R Protein (Recombinant 6His, N-terminus) (aa242-485) - LS-G25515

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

30.0 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Mouse IL22RA1 / IL22R Protein (Recombinant His-T7) (aa258-552) - LS-G25514

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.4 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Rat IL22RA1 / IL22R Protein (Recombinant Fc) (Met1-Ala228) - LS-G98422

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

50.8 kDa

Price:

50 µg/$499

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IL22RA1 / IL22R Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110663

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.9 kDa

Price:

100 µg/$494

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Human IL22RA1 / IL22R Protein (Recombinant GST) (Full Length) - LS-G34844

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

86.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IL22RA1 / IL22R Protein (Recombinant His-SUMO) (aa250-573) - LS-G21808

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

50.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human IL22RA1 / IL22R Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G63024

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL22RA1 / IL22R Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84737

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.9 kDa

Price:

20 µg/$150

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