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IL21

interleukin 21

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Gene Name: interleukin 21
Family/Subfamily: Interleukin
Synonyms: IL21, Interleukin 21, Interleukin-21, Interleukin-21 isoform, Za11, IL-21
Target Sequences: NM_021803 NP_068575.1 Q9HBE4

Publications (3)

1
Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients. Maehara T, Moriyama M, Hayashida JN, Tanaka A, Shinozaki S, Kubo Y, Matsumura K, Nakamura S. Clinical and experimental immunology. 2012 169:89-99. (IHC; Human) [Full Text Article] [PubMed:22774983] [PMC:PMC3406368] Related Antibodies: LS-B1364.
2
CD4 T cell-intrinsic role for the T helper 17 signature cytokine IL-17: Effector resistance to immune suppression. Michael P Crawford, Sushmita Sinha, Pranav S Renavikar, Nicholas Borcherding, Nitin J Karandikar. Proceedings of the National Academy of Sciences of the United States of America. 2020 August;117:19408-19414. [Full Text Article] [PubMed:32719138] [PMC:PMC7430972] Related Antibodies: LS-C104584.
3
Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. Maehara T, Moriyama M, Nakashima H, Miyake K, Hayashida JN, Tanaka A, Shinozaki S, Kubo Y, Nakamura S. Annals of the rheumatic diseases. 2012 Dec;71:2011-19. [Full Text Article] [PubMed:22753386] Related Antibodies: LS-B1364.

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Products
ELISA Kits (42)
Custom (5)
Development Kit (3)
Sandwich (26)
Sandwich CLIA (8)
IL21 (42)
Human (13)
Mouse (15)
Rat (8)
Bovine (1)
Dog (1)
Pig (1)
Rabbit (1)
Sheep (1)
Product Group
DevKit Core (3)
1000 Wells (2)
12 x 8-Well Microstrips (4)
200 Wells (1)
96-Well Microplate (10)
96-Well Strip Plate (25)
No (42)
Cell Culture Supernatants (13)
Cell Lysates (9)
Plasma (32)
Serum (34)
Tissue Homogenates (10)
IL21 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
1.37 - 1000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
IL21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
IL21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IL21 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
IL21 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
1.37 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$990
IL21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
IL21 ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
46 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$479
IL21 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.3 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
IL21 ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
IL21 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
IL21 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$685
IL21 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$685
IL21 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
IL21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IL21 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
11 - 750 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$649
IL21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
IL21 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
11 - 750 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$649
IL21 ELISA Kit
Select
Development Kit
1000 Wells
Human
46 - 3000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
IL21 ELISA Kit
Select
Development Kit
1000 Wells
Mouse
46 - 3000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
IL21 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$795
IL21 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IL21 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IL21 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IL21 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
IL21 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$669
Viewing 1-25 of 42 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).