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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL21 Receptor

Interleukin 21 Receptor

IL21 Receptor is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Gene Name: Interleukin 21 Receptor
Family/Subfamily: Interleukin
Synonyms: IL21R, CD360, Interleukin 21 receptor, Interleukin-21 receptor, NILR, IL-21 receptor, CD360 antigen, IL-21R, IL21 Receptor, Novel interleukin receptor
Target Sequences: NM_021798 NP_068570.1 Q9HBE5

Filtered by: None
Target
IL21 Receptor (47)
Reactivity
Human (37)
Mouse (15)
Rat (6)
Cynomolgus (2)
Monkey (1)
Application
IHC (11)
IHC-P (4)
WB (28)
Flo (6)
ELISA (23)
IF (3)
Peptide-ELISA (1)
Host
rabbit (41)
mouse (1)
goat (2)
rat (3)
Isotype
IgG (19)
IgG2a,k (3)
Clonality
monoclonal mc (4)
polyclonal pc (43)
Clone
4A9 (3)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (3)
Unconjugated (33)
Epitope
aa23-185 (8)
aa35-64 (3)
aa131-165 (1)
aa20-32 (1)
aa35-65 (1)
aa65-80 (1)
aa97-111 (1)
Publications
No (47)
Showing 1-25 of 47 results

IHC-plus™ IL21 Receptor Antibody LS-B572
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-IL21 Receptor antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of IL-21 Receptor in Rat Lung cells with IL-21 Receptor antibody at 20 ug/ml.

IL21 Receptor Antibody (aa35-64) LS-C83977
Rabbit Polyclonal to Mouse IL21 Receptor
Mouse
ELISA, Flo, IHC
Unconjugated
200µg  $455.00

IL21 Receptor Antibody (clone 4A9) LS-C106904
Rat Monoclonal [clone 4A9] (IgG2a,k) to Mouse IL21 Receptor
Mouse
Flo
Unconjugated
50µg  $195.00; 100µg  $275.00; 500µg  $385.00
Staining of 2 day anti-CD3 stimulated BALB/c splenocytes with APC anti-mouse CD4 (GK1.5) (LS-C107336) and Purified Rat IgG2a isotype control followed by Biotin Anti-Rat IgG then SAv-PE. Total viable cells were used for analysis.
Staining of 2 day anti-CD3 stimulated BALB/c splenocytes with APC anti-mouse CD4 (GK1.5) (LS-C107336) and 0.25 ug of Purified anti-mouse IL-21R antibody followed by Biotin Anti-Rat IgG then SAv-PE. Total viable cells were used for analysis.

IL21 Receptor Antibody (clone 4A9, Biotin) LS-C106420
Rat Monoclonal [clone 4A9] (IgG2a,k) to Mouse IL21 Receptor
Mouse
Flo
Biotin Conjugated
50µg 0.5mg/ml  $225.00; 100µg 0.5mg/ml  $275.00; 500µg  $455.00
Staining of C57Bl/6 splenocytes with 0.25 ug of Biotin Rat IgG2a isotype control (open histogram) or 0.25 ug of Biotin anti-mouse IL-21R antibody (colored histogram) followed by SAv-PE. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL21 Receptor Antibody (clone 4A9, PE) LS-C106102
Rat Monoclonal [clone 4A9] (IgG2a,k) to Mouse IL21 Receptor
Mouse
Flo
PE Conjugated
50µg 0.2mg/ml  $245.00; 100µg  $305.00; 200µg 0.2mg/ml  $375.00
Staining of BALB/c splenocytes with 0.25 ug of PE Rat IgG2a isotype control (open histogram) or PE anti-mouse IL-21R antibody (colored histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL21 Receptor Antibody (aa35-64) LS-C83985
Rabbit Polyclonal to Mouse IL21 Receptor
Mouse
ELISA, Flo, IHC
Unconjugated
200µg  $455.00

IL21 Receptor Antibody (aa65-80) LS-C723
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Human, Monkey
ELISA, WB
Unconjugated
100µg 200µl 0.5mg/ml  $335.00
Western blot of IL-21R in 30 ugs of Raji cell lysate using antibody at 1 ug/ml.

IL21 Receptor Antibody (aa35-64) LS-C83978
Goat Polyclonal to Human IL21 Receptor
Human
ELISA, IHC
Unconjugated
200µg  $455.00

IL21 Receptor Antibody LS-C666401
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Human
ELISA, Flo, IHC, WB
Unconjugated
100µg  $355.00

IL21 Receptor Antibody LS-C675891
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100

IL21 Receptor Antibody LS-C803934
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

IL21 Receptor Antibody LS-C403
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
0.1mg  $365.00
Immunofluorescence of IL-21 Receptor in A431 cells with IL-21 Receptor antibody at 20 ug/ml.  Green: IL-21 Receptor Antibody  Blue: DAPI staining
Western blot of IL-21R expression in human Raji cell lysate with IL-21R antibody at 1 ug /ml.

IL21 Receptor Antibody LS-C675890
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100

IL21 Receptor Antibody LS-C412935
Rabbit Polyclonal to Human IL21 Receptor
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl  $385.00

IL21 Receptor Antibody LS-C349310
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cell lines.

IL21 Receptor Antibody LS-C403795
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Human
ELISA, IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human lung cancer using IL21R Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human lung cancer using IL21R Polyclonal Antibody at dilution of 1:40.

IL21 Receptor Antibody LS-C400527
Rabbit Polyclonal (IgG) to Human IL21 Receptor
Human
ELISA, IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human lung cancer using IL21R Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human lung cancer using IL21R Polyclonal Antibody at dilution of 1:40.

IL21 Receptor Antibody LS-C779525
Rabbit Polyclonal to Human IL21 Receptor
Mouse, Human
ELISA, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00

IL21 Receptor Antibody (aa131-165) LS-C393008
Rabbit Polyclonal to Human IL21 Receptor
Human
Peptide-ELISA, WB
Unconjugated
200µl  $325.00
Anti-IL21R Antibody (N-Term) at 1:2000 dilution + A2058 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 59 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

IL21 Receptor Antibody LS-C487534
Rabbit Polyclonal to Mouse IL21 Receptor
Mouse
ELISA
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

IL21 Receptor Antibody (aa35-65) LS-C187850
Goat Polyclonal (IgG) to Human IL21 Receptor
Human
ELISA, IHC-P
Unconjugated
0.1mg  $425.00
Immunohistochemistry of paraffin-embedded human lung with Goat anti-human interleukin-21 receptor (N-terminal)

IL21 Receptor Antibody LS-C487536
Rabbit Polyclonal to Mouse IL21 Receptor
Mouse
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00

IL21 Receptor Antibody LS-C487533
Mouse Monoclonal to Human IL21 Receptor
Human
ELISA
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

IL21 Receptor Antibody LS-C487537
Rabbit Polyclonal to Human IL21 Receptor
Human
ELISA
Unconjugated
50µl  $275.00; 100µl  $355.00

IL21 Receptor Antibody LS-C487543
Rabbit Polyclonal to Human IL21 Receptor
Human
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00
Showing 1-25 of 47 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).