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IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Gene Name: | interleukin 20 |
Family/Subfamily: | Hormone , not assigned-Hormone |
Synonyms: | IL20, Cytokine Zcyto10, Four alpha helix cytokine, IL10D, Interleukin 20, IL-20, Interleukin-20, ZCYTO10 |
Target Sequences: | NM_018724 NP_061194.2 Q9NYY1 |
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