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IL1RL2

interleukin 1 receptor-like 2

Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Gene Name: interleukin 1 receptor-like 2
Family/Subfamily: Interleukin
Synonyms: IL1RL2, IL-1Rrp2, IL1R-rp2, IL1RRP2, Interleukin 1 receptor-like 2, Interleukin-1 receptor-like 2, IL-36R
Target Sequences: NM_003854 NP_003845.2 Q9HB29

Publications (1)

1
Interleukin-38 promotes skin tumorigenesis in an IL-1Rrp2-dependent manner. Hong Zhou , Qixiang Zhao , Chengcheng Yue , Jiadong Yu , Huaping Zheng, Jing Hu, Zhonglan Hu, Haozhou Zhang, Xiu Teng, Xiao Liu, Xiaoqiong Wei, Yuxi Zhou, Fanlian Zeng, Yan Hao, Yawen Hu, Xiaoyan Wang, Chen Zhang, Linna Gu, Wenling Wu, Yifan Zhou, Kaijun Cui, Nongyu Huang, Wei Li, Zhen Wang, Jiong Li. EMBO reports. 2022 June;23:e53791. [Full Text Article] [PubMed:35578812] [PMC:PMC9171418] Related Antibodies: LS-B10135.

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Products
Antibodies (23)
Primary (23)
IL1RL2 (23)
Human (23)
Mouse (2)
Rat (1)
Dog (3)
Horse (3)
IHC (2)
IHC-P (2)
WB (19)
Flo (8)
ELISA (12)
IF (1)
Peptide-ELISA (1)
rabbit (21)
mouse (2)
Product Group
IHCPlus (2)
IgG (14)
IgG2b (2)
monoclonal mc (2)
polyclonal pc (21)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (12)
aa257-286 (7)
aa107-156 (4)
No (22)
Yes (1)
IL1RL2 Antibody - Anti-IL1RL2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
IL1RL2 Antibody - Anti-IL1RL2 antibody IHC staining of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
IL1RL2 Antibody - Fig-1: Western blot analysis of IL-36R. Anti-IL-36R antibody was tested at 2 µg/ml on human Small Intestine lysate.
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IL1RL2 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
25 µg/$288; 100 µg/$414
IL1RL2 Antibody - IL1RL2 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1RL2 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
IL1RL2 Antibody - IL1RL2 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1RL2 Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody
Dog, Horse, Human
WB
HRP Conjugated
100 µl/$469
IL1RL2 Antibody - IL1RL2 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1RL2 Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody
Dog, Horse, Human
WB
Biotin Conjugated
100 µl/$469
IL1RL2 Antibody - IL1RL2 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1RL2 Rabbit anti-Human Polyclonal (aa107-156) (FITC) Antibody
Dog, Horse, Human
WB
FITC Conjugated
100 µl/$469
IL1RL2 Antibody - Western blot analysis of extracts of various cell lines, using IL1RL2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$351
IL1RL2 Antibody - Fig-1: Western blot analysis of IL-36R. Anti-IL-36R antibody was tested at 2 µg/ml on human Small Intestine lysate.
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IL1RL2 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
25 µg/$288; 100 µg/$414
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) Antibody
Human
Flo, WB
Unconjugated
200 µl/$734
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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IL1RL2 Rabbit anti-Human Polyclonal (aa257-286) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
IL1RL2 Antibody - Western blot analysis ILRL2 using HuvEc whole cells lysates
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL1RL2 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using IL1RL2 Antibody at dilution of 1:100
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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IL1RL2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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IL1RL2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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IL1RL2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
IL1RL2 Antibody
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IL1RL2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
Viewing 1-23 of 23 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).