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IL1A / IL-1 Alpha

interleukin 1, alpha

IL1A / IL-1 Alpha is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Gene Name: interleukin 1, alpha
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha
Target Sequences: NM_000575 NP_000566.3 P01583

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Products
Proteins (50)
Over-Expression Lysate (2)
Recombinant (48)
IL1A / IL-1 Alpha (50)
Product Group
Coronavirus Antibodies Proteins cDNAs (50)
Cytokine Release Syndrome (50)
Cytokine Release Syndrome Proteins (50)
Animal-free (1)
No (50)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (9)
His, N-Terminal (1)
His-S (2)
His-SUMO (1)
His-T7 (6)
Myc-DDK (Flag) (2)
Bovine (2)
Dog (2)
Goat (1)
Guinea pig (1)
Horse (1)
Human (20)
Mouse (11)
Pig (1)
Rabbit (2)
Rat (5)
Rhesus monkey (3)
293T Cells (1)
CHO Cells (1)
E. coli (41)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Yeast (3)
Purified (17)
Low endotoxin level (22)
Biologically active (16)
Animal-free (1)
IL1A / IL-1 Alpha Protein - Recombinant Interleukin 1 Alpha By SDS-PAGE
Select
E. coli
His
16.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Select
E. coli
His
Less than 0.1 EU/µg protein (determined by LAL method).
50 µg/$541; 10 µg/$337
IL1A / IL-1 Alpha Protein
Select
E. coli
None
Biologically active
18.1 kDa
10 µg/$388; 100 µg/$1,359; 500 µg/$2,723
IL1A / IL-1 Alpha Protein - Recombinant Interleukin 1 Alpha By SDS-PAGE
Select
E. coli
His-S
16.5 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
IL1A / IL-1 Alpha Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
30.4 kDa
100 µg/$494
IL1A / IL-1 Alpha Protein - Recombinant Bovine interleukin-1 alpha detected using Rabbit anti Bovine interleukin-1 alpha as the capture reagent and Rabbit anti Bovine interleukin-1 alpha:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
17.1 kDa
5 µg/$390
IL1A / IL-1 Alpha Protein - Recombinant Rabbit interleukin-1 alpha detected using Goat anti Rabbit interleukin-1 alpha as the capture reagent and Goat anti Rabbit interleukin-1 alpha:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
17.8 kDa
5 µg/$390
IL1A / IL-1 Alpha Protein - Active Interleukin 1 Alpha (IL1a) by WB
Select
E. coli
His, N-Terminal
21kDa
10 µg/$339; 50 µg/$802; 200 µg/$1,430; 100 µg/$1,214; 1 mg/$2,728; 500 µg/$2,223; 5 mg/$5,601; 2 mg/$2,988
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).
The 156 amino acid recombinant protein has a predicted molecular mass of 17,990 Da. The DTT-reduced and the non-reduced protein migrate at approximately 18kDa by SDS-PAGE. The N-terminal amino acid is Serine.
10 µg/$344; 25 µg/$436; 100 µg/$969; 500 µg/$2,133
IL1A / IL-1 Alpha Protein - Human IL-1α induces the proliferation of D10.G4.1 mouse helper T lymphocytes.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).
The 159 amino acid recombinant protein has a predicted molecular mass of 18,047 Da. The DTT-reduced and the non-reduced protein migrate at approximately 18kDa by SDS-PAGE. The N-terminal amino acid is Serine.
10 µg/$359; 25 µg/$512; 100 µg/$1,097; 500 µg/$2,133
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
17.9 kDa
10 µg/$364; 1 mg/$4,545
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
18.0 kDa
10 µg/$364; 1 mg/$4,545
IL1A / IL-1 Alpha Protein
Select
E. coli
His-SUMO
34.12 kD
1 mg/$1,679; 100 µg/$598; 20 µg/$405
IL1A / IL-1 Alpha Protein - 12.5% SDS-PAGE of human IL1A stained with Coomassie Blue
Select
Wheat Germ Extract
GST
57 kDa
10 µg/$479; 25 µg/$670
IL1A / IL-1 Alpha Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
His-T7
20.4 kDa
10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304
IL1A / IL-1 Alpha Protein - Recombinant  Interleukin 1 Alpha By SDS-PAGE
Select
E. coli
His-S
23.3 kDa
10 µg/$290; 50 µg/$497; 100 µg/$795; 200 µg/$992; 1 mg/$2,134; 500 µg/$1,658; 5 mg/$3,473; 2 mg/$2,324
IL1A / IL-1 Alpha Protein - Recombinant  Interleukin 1 Alpha By SDS-PAGE
Select
E. coli
His-T7
23.4 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
IL1A / IL-1 Alpha Protein - Recombinant  Interleukin 1 Alpha By SDS-PAGE
Select
E. coli
His-T7
23.3 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
IL1A / IL-1 Alpha Protein - Recombinant Interleukin 1 Alpha By SDS-PAGE
Select
E. coli
His-T7
21.5 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
IL1A / IL-1 Alpha Protein
Select
Yeast
His
20.13 kD
100 µg/$679; 20 µg/$429; 1 mg/$1,973
IL1A / IL-1 Alpha Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
20.3 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
IL1A / IL-1 Alpha Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
IL1A / IL-1 Alpha Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
30.4 kDa
20 µg/$150
IL1A / IL-1 Alpha Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
Viewing 1-25 of 50 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).