IL17C

interleukin 17C

Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.

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Products

ELISA Kits (12)

Type

Custom (1)

Sandwich (9)

Sandwich CLIA (2)

Target

IL17C (12)

Reactivity

Human (7)

Mouse (5)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (9)

Publications

No (12)

Sample Type

Cell Culture Supernatants (7)

Cell Lysates (3)

Plasma (11)

Serum (11)

Tissue Homogenates (3)

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Mouse IL17C (CLIA) ELISA Kit - LS-F26142

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$990

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Human IL17C (Sandwich ELISA) ELISA Kit - LS-F8259

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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Human IL17C (Sandwich ELISA) ELISA Kit - LS-F66925

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human IL17C (CLIA) ELISA Kit - LS-F26141

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$968

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Human IL17C (Sandwich ELISA) ELISA Kit - LS-F31456

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$669

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Mouse IL17C (Sandwich ELISA) ELISA Kit - LS-F31492

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

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Human IL17C (Sandwich ELISA) ELISA Kit - LS-F54641

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Mouse IL17C (Custom) ELISA Kit - LS-F65968

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

Select

Mouse IL17C (Sandwich ELISA) ELISA Kit - LS-F6636

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

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Human IL17C (Sandwich ELISA) ELISA Kit - LS-F10486

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$1,150

Select

Mouse IL17C (Sandwich ELISA) ELISA Kit - LS-F10487

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$1,150

Select

Human IL17C (Sandwich ELISA) ELISA Kit - LS-F641

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$618

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