IL17C

interleukin 17C

Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.

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Antibodies (38)

ELISA Kits (12)

Proteins (7)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (38)

Recombinant (5)

Sandwich (9)

Sandwich CLIA (2)

Target

IL17C (57)

Reactivity

Human (35)

Mouse (17)

Rat (1)

Primate (1)

Application

IHC (5)

IHC-P (2)

WB (35)

Flo (1)

ELISA (7)

IP (1)

Peptide-ELISA (2)

Host

rabbit (34)

mouse (2)

goat (1)

rat (1)

Isotype

IgG (13)

IgG1,k (1)

IgG2a (1)

Clonality

monoclonal mc (2)

polyclonal pc (36)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (9)

APC (2)

APC Conjugated (3)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (3)

Unconjugated (19)

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Epitope

aa36-187 (8)

aa7-159 (8)

aa80-130 (1)

Publications

No (57)

Sample Type

Cell Culture Supernatants (7)

Cell Lysates (3)

Plasma (11)

Serum (11)

Tissue Homogenates (3)

Tag

GST (1)

His, N-Terminal (1)

His-GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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IL17C Antibody LS-C406475

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IL17C Antibody LS-C502328

Antibody:

IL17C Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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Mouse IL17C (CLIA) ELISA Kit - LS-F26142

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$871

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IL17C Antibody LS-C70965

Antibody:

IL17C Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µg/$872

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IL17C Antibody LS-C807514

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IL17C Antibody LS-C308446

Antibody:

IL17C Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$705

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IL17C Antibody LS-C403239

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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Human IL17C (Sandwich ELISA) ELISA Kit - LS-F8259

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

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Human IL17C Protein (Recombinant His-GST, N-terminus) - LS-G15248

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

20.7 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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IL17C Antibody LS-C813884

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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IL17C Antibody LS-C662609

Antibody:

IL17C Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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IL17C Antibody LS-C662607

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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IL17C Antibody LS-C778683

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

100 µg/$357

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IL17C Antibody LS-C310741

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

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IL17C Antibody (aa7-159) LS-C294864

Antibody:

IL17C Rabbit anti-Mouse Polyclonal (aa7-159) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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IL17C Antibody (aa7-159, HRP) LS-C712410

Antibody:

IL17C Rabbit anti-Mouse Polyclonal (aa7-159) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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IL17C Antibody (aa7-159, Biotin) LS-C687809

Antibody:

IL17C Rabbit anti-Mouse Polyclonal (aa7-159) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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IL17C Antibody (aa7-159, FITC) LS-C694700

Antibody:

IL17C Rabbit anti-Mouse Polyclonal (aa7-159) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IL17C Antibody LS-C783142

Antibody:

IL17C Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$288; 100 µg/$414

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IL17C Antibody LS-C487346

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$412

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IL17C Antibody LS-C310746

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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IL17C Antibody LS-C497297

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IL17C Antibody (aa80-130) LS-C359404

Antibody:

IL17C Rabbit anti-Human Polyclonal (aa80-130) Antibody

Reactivity:

Human, Primate

Applications:

WB

Format:

Unconjugated

Price:

0.1 mg/$386

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IL17C Antibody LS-C668732

Antibody:

IL17C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

IL17C Antibody (aa36-187) LS-C294862

Antibody:

IL17C Rabbit anti-Human Polyclonal (aa36-187) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561

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