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IL16

interleukin 16

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Gene Name: interleukin 16
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL16, IL-16, Interleukin 16, Neuronal interleukin 16, PrIL-16, NIL16, HsT19289, LCF, PRIL16, Pro-interleukin-16, Prointerleukin 16
Target Sequences: NM_004513 NP_004504.3 Q14005

☰ Filters
Products
Proteins (32)
Over-Expression Cell Culture Supernatant (2)
Over-Expression Lysate (4)
Recombinant (26)
IL16 (32)
Animal-free (1)
No (32)
6His, N-terminus (5)
GST (1)
His (2)
His, N-Terminal (5)
His-T7 (3)
Myc-DDK (Flag) (3)
Bovine (1)
Human (20)
Mouse (8)
Rat (1)
Rhesus monkey (1)
293T Cells (1)
E. coli (23)
HEK 293 Cells (7)
Wheat Germ Extract (1)
Purified (11)
Low endotoxin level (10)
Biologically active (9)
Animal-free (1)
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
13.5 kDa
2 µg/$268; 10 µg/$349
Select
HEK 293 Cells
His, N-Terminal
~13 kDa
200 µl/$283
Select
HEK 293 Cells
His, N-Terminal
~13 kDa
100 µg/$298
IL16 Protein - Active Interleukin 16 (IL16) by WB
Select
E. coli
His, N-Terminal
17kDa
10 µg/$362; 50 µg/$902; 200 µg/$1,553; 100 µg/$1,325; 1 mg/$2,881; 500 µg/$2,369; 5 mg/$6,301; 2 mg/$3,361
Select
E. coli
None
Less than 1 EU/µg (determined by LAL method).
13.4 kDa
10 µg/$364; 1 mg/$4,545; 50 µg/$754
IL16 Protein - 12.5% SDS-PAGE of human IL16 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
74.8 kDa
10 µg/$479; 25 µg/$670
IL16 Protein - Recombinant Interleukin 16 By SDS-PAGE
Select
E. coli
His
16.0 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
Select
HEK 293 Cells
6His, N-terminus
14 kDa
100 µg/$298
Select
HEK 293 Cells
6His, N-terminus
14 kDa
200 µl/$283
IL16 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
14 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
IL16 Protein - Purified recombinant protein IL16 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
66.5 kDa
20 µg/$1,107
IL16 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
66.5 kDa
20 µg/$215
IL16 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
66.5 kDa
100 µg/$710
IL16 Protein
Select
E. coli
None
50 µg/$411; 250 µg/$985; 10 µg/$276
IL16 Protein
Select
E. coli
None
Biologically active
12.5 kDa
10 µg/$388; 100 µg/$1,661; 500 µg/$3,629
IL16 Protein
Select
E. coli
None
Biologically active
12.2 kDa
10 µg/$388; 100 µg/$1,661; 500 µg/$3,629
IL16 Protein
Select
E. coli
None
Biologically active
13.4 kDa
10 µg/$388; 100 µg/$1,466; 500 µg/$3,025
IL16 Protein
Select
E. coli
None
Biologically active
12.4 kDa
10 µg/$388; 100 µg/$1,466; 500 µg/$3,025
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
12.4 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$282; 10 µg/$370
IL16 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
His, N-Terminal
17 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484
IL16 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
13.4 kDa
50 µg/$698; 10 µg/$356; 1 mg/$3,404; 500 µg/$2,385
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
14.5 kDa
10 µg/$288; 50 µg/$436
IL16 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.4 kDa
10 µg/$317; 50 µg/$524
Viewing 1-25 of 32 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).