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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL12RB2

interleukin 12 receptor, beta 2

IL12RB2 is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Gene Name: interleukin 12 receptor, beta 2
Family/Subfamily: Interleukin
Synonyms: IL12RB2, Il-12R beta2, IL-12R-beta-2, IL-12 receptor beta 2, Il-12 receptor beta2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, RP11-102M16.1, IL-12RB2
Target Sequences: NM_001559 NP_001550.1 Q99665

Filtered By: None
Target
IL12RB2 (69)
Reactivity
Human (48)
Mouse (26)
Rat (5)
Bovine (4)
Chimpanzee (3)
Pig (4)
Application
IHC (42)
IHC-P (1)
WB (59)
Flo (10)
ELISA (13)
IF (1)
Host
rabbit (64)
mouse (5)
Isotype
IgG (58)
IgG1 (2)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (4)
polyclonal pc (65)
Clone
2H6 (1)
305719 (1)
Format
AP Conjugated (2)
APC (4)
APC Conjugated (7)
Azide-free (1)
Biotin Conjugated (9)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (10)
HRP Conjugated (8)
PE Conjugated (7)
Unconjugated (18)
Epitope
aa559-647 (17)
aa285-441 (10)
aa455-606 (8)
aa756-783 (8)
aa326-375 (4)
aa24-622 (2)
aa323-695 (1)
Publications
No (69)
Showing 1-25 of 69 results

IL12RB2 Antibody (aa756-783) IHC-plus™ LS-B10479
Rabbit Polyclonal to Human IL12RB2
Human
Flo IHC IHC-P WB
Unconjugated
200µl  $425.00
Anti-IL12RB2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
IL12RB2 Antibody western blot of MDA-MB435 cell line lysates (35 ug/lane). The IL12RB2 antibody detected the IL12 protein (arrow).
Anti-IL12RB2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
IL12RB2 Antibody western blot of MDA-MB435 cell line lysates (35 ug/lane). The IL12RB2 antibody detected the IL12 protein (arrow).

IL12RB2 Antibody (aa24-622, PE) LS-C125812
Mouse Monoclonal (IgG1) to Human IL12RB2
Mouse, Human
Flo
PE Conjugated
100tst 0.01mg/ml  $680.00

IL12RB2 Antibody (aa24-622, clone 305719, APC) LS-C125813
Mouse Monoclonal [clone 305719] (IgG1) to Human IL12RB2
Human
Flo
APC Conjugated
100tst 0.025mg/ml  $680.00

IL12RB2 Antibody (aa756-783) LS-C322201
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
Unconjugated
200µl  $530.00

IL12RB2 Antibody (aa756-783, Biotin) LS-C215241
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $680.00

IL12RB2 Antibody (aa756-783, FITC) LS-C215242
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
FITC Conjugated
200µl 0.55mg/ml  $680.00

IL12RB2 Antibody (aa756-783, AP) LS-C215239
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

IL12RB2 Antibody (aa756-783, APC) LS-C215240
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

IL12RB2 Antibody (aa756-783, Azide-free, HRP) LS-C215244
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

IL12RB2 Antibody (aa756-783, PE) LS-C215245
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA Flo IHC WB
PE Conjugated
200µl  $680.00

IL12RB2 Antibody (aa285-441) LS-C294829
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $515.00; 10ml 0.5mg/ml  $2,040.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa285-441, Biotin) LS-C685420
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $560.00; 10ml  $2,250.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa285-441, FITC) LS-C691901
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
FITC Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $325.00; 1ml  $620.00; 10ml  $2,460.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa285-441, Cy3) LS-C699945
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $435.00; 1ml  $1,020.00; 10ml  $4,095.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody LS-C143930
Mouse Monoclonal (IgG2a) to Human IL12RB2
Human
WB
Unconjugated
100µg  $620.00

IL12RB2 Antibody (aa455-606) LS-C294830
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $515.00; 10ml 0.5mg/ml  $2,040.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa455-606, Biotin) LS-C299860
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
Biotin Conjugated
100µl 0.5mg/ml  $365.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa455-606, FITC) LS-C304743
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
FITC Conjugated
100µl 0.5mg/ml  $385.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa455-606, Cy3) LS-C699946
Rabbit Polyclonal (IgG) to Mouse IL12RB2
Mouse
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $435.00; 1ml  $1,020.00; 10ml  $4,095.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody LS-C672013
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA IF
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunofluorescence staining of HepG2 cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
Immunofluorescence staining of HepG2 cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

IL12RB2 Antibody (aa559-647) LS-C294828
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $495.00; 10ml 0.5mg/ml  $1,980.00
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IL12RB2 Antibody (aa559-647) LS-C372655
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $495.00; 10ml 0.5mg/ml  $1,980.00
Western blot of IL12RB2 antibody.
Western blot of IL12RB2 antibody.

IL12RB2 Antibody LS-C403238
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human thyroid cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human thyroid cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human thyroid cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.

IL12RB2 Antibody LS-C406474
Rabbit Polyclonal (IgG) to Human IL12RB2
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human prostate cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human prostate cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human prostate cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human prostate cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.

IL12RB2 Antibody (clone 2H6) LS-C197525
Mouse Monoclonal [clone 2H6] (IgG2a,k) to Human IL12RB2
Human
ELISA WB
Unconjugated
100µg  $355.00
Detection limit for recombinant GST tagged IL12RB2 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged IL12RB2 is approximately 1 ng/ml as a capture antibody.
Showing 1-25 of 69 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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