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IL-22BP / IL22RA2

interleukin 22 receptor, alpha 2

Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.Isoform 1 may play a role in establishing and maintaining successful pregnancy.

Gene Name: interleukin 22 receptor, alpha 2
Synonyms: IL22RA2, Class II cytokine receptor, IL-22BP, IL-22RA2, IL-22R-alpha-2, Interleukin 22-binding protein, Interleukin-22-binding protein, CRF2-10, CRF2-S1, CRF2X, IL-22 receptor subunit alpha-2, IL22BP, ZcytoR16
Target Sequences: NM_052962 NP_443194.1 Q969J5

☰ Filters
Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
IL-22BP / IL22RA2 (11)
Bind (1)
SDS-PAGE (1)
No (11)
6His, C-terminus (2)
6His, N-terminus (1)
Fc, C-terminus (2)
His,C-terminus (2)
His-Fc (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (8)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Human Cells (3)
Mammalian Cells (2)
Purified (1)
Low endotoxin level (7)
Biologically active (1)
IL-22BP / IL22RA2 Protein - Recombinant  Interleukin 22 Receptor Alpha 2 By SDS-PAGE
Select
E. coli
His-T7
26.4 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
IL-22BP / IL22RA2 Protein - Recombinant Interleukin 22 Receptor Alpha 2 By SDS-PAGE
Select
E. coli
6His, N-terminus
27.3 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
IL-22BP / IL22RA2 Protein - Immobilized IL22BP-His at 10 µg/ml (100 µl/well) can bind biotinylated IL22, The EC50 of biotinylated IL22 is 1.78-4.14 ng/ml.
Select
HEK 293 Cells
His,C-terminus
Bind SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant human IL22RA2 comprises 221 amino acids with a predicted molecular mass of 26.1 kDa. As a result of glycosylation, rh IL22RA2 migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions.
50 µg/$395; 1 mg/$2,333
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.8kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
IL-22BP / IL22RA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.8 kDa
20 µg/$150
Select
Human Cells
His-Fc
Less than 1.0 EU/µg protein (determined by LAL method).
52.8 kDa
50 µg/$721
IL-22BP / IL22RA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.8 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7 kDa
10 µg/$288; 50 µg/$436
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.8 kDa
10 µg/$288; 50 µg/$436
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.1 kDa
50 µg/$721
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).