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Unfortunately, the antibody (ID:416432) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



IL-1B / IL-1 Beta

interleukin 1, beta

IL-1 Beta is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Gene Name: interleukin 1, beta
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL1B, IL-1B, IL-1 beta, IL1-BETA, Preinterleukin 1 beta, Pro-interleukin-1-beta, Catabolin, IL-1, IL1F2, Interleukin 1, beta, Interleukin-1 beta
Target Sequences: NM_000576 NP_000567.1 P01584

Publications (8)

1
Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4’-geranyloxyferulic acid. Takuji Tanaka, Mariangela B.M. de Azevedo, Nelson Dura´n, Joel B. Alderete, Francesco Epifano, Salvatore Genovese, Mayu Tanaka, Takahiro Tanaka, Massimo Curini. International journal of cancer. Journal international du cancer. 2010 126:830-40. (IHC-P; Mouse) [Full Text Article] [PubMed:19688830]
2
Trimeric form of intracellular ATP synthase subunit of Aggregatibacter actinomycetemcomitans binds human interleukin-1. Paino A, Tuominen H, Jskelinen M, Alanko J, Nuutila J, Asikainen SE, Pelliniemi LJ, Pllnen MT, Chen C, Ihalin R. PloS one. 2011 6:e18929. [PubMed:21533109] [PMC:PMC3078924]
3
Interleukin-1 is internalised by viable Aggregatibacter actinomycetemcomitans biofilm and locates to the outer edges of nucleoids. Paino A, Lohermaa E, Sormunen R, Tuominen H, Korhonen J, Pllnen MT, Ihalin R. Cytokine. 2012 60:565-74. (IHC, EM; Bacteria) [PubMed:22898394]
4
Serum soluble interleukin 7 receptor is strongly associated with lupus nephritis in patients with systemic lupus erythematosus. Badot V, Luijten RK, van Roon JA, Depresseux G, Aydin S, Van den Eynde BJ, Houssiau FA, Lauwerys BR. Annals of the rheumatic diseases. 2013 72:453-6. (IHC-Fr; Human) [PubMed:23264357] Related Antibodies: LS-C18827.
5
Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo. Smolders S, Smolders SM, Swinnen N, Gärtner A, Rigo JM, Legendre P, Brône B. Frontiers in cellular neuroscience. 2015 9:301. (Flo; Mouse) [Full Text Article] [PubMed:26300736] [PMC:PMC4525016] Related Antibodies: LS-C184791.
6
Effect of Roux-en-Y Gastric Bypass on the NLRP3 Inflammasome in Adipose Tissue from Obese Rats. Mocanu AO, Mulya A, Huang H, Dan O, Shimizu H, Batayyah E, Brethauer SA, Dinischiotu A, Kirwan JP. PloS one. 2015 10:e0139764. (IHC; Rat) [Full Text Article] [PubMed:26437377] [PMC:PMC4593548] Related Antibodies: LS-C104781.
7
p65-Dependent production of interleukin-1 beta by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts. Schulze J, Weber K, Baranowsky A, Streichert T, Lange T, Spiro AS, Albers J, Seitz S, Zustin J, Amling M, Fehse B, Schinke T. Cancer letters. 2012 Apr;317:106-13. [Full Text Article] [PubMed:22108531] Related Antibodies: LS-C18827.
8
Ontogeny and the effects of in utero brain ischemia on interleukin-1 beta and interleukin-6 protein expression in ovine cerebral cortex and white matter. Sadowska GB, Threlkeld SW, Flangini A, Sharma S, Stonestreet BS. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2012 Oct;30:457-63. [Full Text Article] [PubMed:22698958] [PMC:PMC3438310] Related Antibodies: LS-C42757.
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Filtered By: None
Target
il-1b-il-1-beta (377)
Reactivity
Human (134)
Mouse (85)
Rat (51)
Bovine (15)
Cat (2)
Chicken (10)
Chimpanzee (3)
Cow (8)
Cynomolgus (2)
Dog (28)
E. coli (1)
Goat (1)
Guinea pig (16)
Horse (21)
Monkey (2)
Pig (31)
Primate (6)
Rabbit (10)
Sheep (20)
Application
IHC (98)
IHC-Fr (4)
IHC-P (11)
WB (312)
Flo (22)
Block (1)
ELISA (139)
FLISA (3)
Func (4)
ICC (17)
IF (3)
Inhb (1)
IP (17)
Neut (38)
Peptide-ELISA (2)
RIA (1)
Host
rabbit (238)
mouse (119)
goat (5)
chicken (1)
guinea pig (9)
hamster (1)
rat (3)
sheep (1)
Isotype
IgG (207)
IgG1 (22)
IgG1,k (7)
IgG2a (3)
IgG2a,k (9)
IgG2b (7)
IgG2b,k (33)
IgM (8)
Clonality
monoclonal mc (122)
polyclonal pc (255)
Clone
11E5 (2)
11n92 (2)
1400.24 (1)
1A7 (1)
2A8 (1)
3A6 (1)
3E1 (1)
43N1F9 (1)
43N1G6 (1)
43N3D8 (1)
43N4C4 (1)
43N8F6 (1)
5C10 (1)
6B1G11 (1)
6D57 (1)
6E10 (2)
7C10B9 (1)
9627 (1)
AS10 (1)
AS56 (1)
B122 (1)
CRM56 (3)
CRM57 (1)
DF8 (1)
H1b-27 (1)
ID4 (1)
Format
AP Conjugated (7)
APC (20)
APC Conjugated (24)
Azide-free (5)
Biotin Conjugated (53)
CF Conjugated (1)
Cy3 Conjugated (20)
Cy7 Conjugated (20)
FITC Conjugated (44)
HRP Conjugated (35)
Magnetic beads Conjugated (2)
PE Conjugated (29)
Sepharose Conjugated (2)
Unconjugated (140)
Epitope
aa118-269 (26)
aa1-266 (18)
aa63-247 (17)
aa103-260 (10)
aa117-269 (10)
aa95-262 (10)
N-Terminus (9)
aa117-268 (9)
aa118-268 (9)
aa148-174 (9)
aa115-266 (8)
Internal (4)
aa249-269 (4)
aa38-87 (4)
aa109-251 (3)
aa211-225 (3)
C-Terminus (1)
aa1-269 (1)
aa113-162 (1)
aa202-229 (1)
aa249-263 (1)
aa250-265 (1)
internal region (1)
Publications
No (373)
Yes (4)
Showing 1-25 out of 377 results
IL-1B / IL-1 Beta Antibody IHC-plus™ LS-B15764
Human Uterus, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of extracts of Mouse liver tissue.

Rabbit Polyclonal (IgG) to Human IL-1B / IL-1 Beta
Mouse, Human
IHC-P WB
Unconjugated
IL-1B / IL-1 Beta Antibody (N-Terminus) LS-C18827
Anti-Human IL-1B Antibody - Western Blot. IL-1B was used at a 1:200 dilution incubated 1 h at room temperature to detect dog IL-1B by Western blot. Lane 1 and 2 were loaded with 2.5 ug and 500 ng of dog IL-1B respectively. The molecular weight of the detected band is estimated by comparison to molecular weight markers (not shown). Detection occurred using a 1:3000 dilution of IRDye800 conjugated Donkey anti-Rabbit IgG (code # for 1h at room temperature. LICORs Odyssey Infrared Imaging System was used to scan and process the image. Other detection systems will yield similar results.

Rabbit Polyclonal to Human IL-1B / IL-1 Beta
Dog, Human, Primate
ELISA IHC IHC-Fr IHC-P IP RIA WB
Unconjugated
IL-1B / IL-1 Beta Antibody LS-C42757

Rabbit Polyclonal (IgG) to Sheep IL-1B / IL-1 Beta
Sheep
ELISA WB
Unconjugated
IL-1B / IL-1 Beta Antibody (clone 3A6) LS-C169431
IHC of paraffin-embedded muscle tissues using IL1B mouse monoclonal antibody with DAB staining.
IHC of paraffin-embedded lung cancer tissues using IL1B mouse monoclonal antibody with DAB staining.

Mouse Monoclonal [clone 3A6] (IgG1) to Human IL-1B / IL-1 Beta
Human
ELISA IF IHC IHC-P WB
Unconjugated
IL-1B / IL-1 Beta Antibody (clone 3E1) LS-C174781
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IL1B mouse monoclonal antibody.
Anti-IL1B mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IL1B.

Mouse Monoclonal [clone 3E1] (IgG1) to Human IL-1B / IL-1 Beta
Human
IF IHC IHC-P WB
Unconjugated
IL-1B / IL-1 Beta Antibody (aa148-174) LS-C165185
Formalin-fixed and paraffin-embedded human lung carcinoma with IL1B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of IL1B Antibody in NCI-H460 cell line lysates (35 ug/lane). IL1B (arrow) was detected using the purified antibody.

Rabbit Polyclonal to Human IL-1B / IL-1 Beta
Human
Flo IHC IHC-P WB
Unconjugated
IL-1B / IL-1 Beta Antibody (clone AS10) LS-C26495

Mouse Monoclonal [clone AS10] (IgG1)
Human
ELISA IHC IP Neut
Unconjugated
IL-1B / IL-1 Beta Antibody (clone DF8, Azide-free) LS-C7686

Mouse Monoclonal [clone DF8] (IgG1) to Pig IL-1B / IL-1 Beta
Pig
WB
Unconjugated, Azide-free
IL-1B / IL-1 Beta Antibody LS-C104781
Western Blot (non-reducing) of IL1B / IL-1 Beta antibody LS-C104781.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of IL1B / IL-1 Beta antibody LS-C104781.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Rat IL-1B / IL-1 Beta
Rat
ELISA Neut WB
Unconjugated
IL-1B / IL-1 Beta Antibody (Biotin) LS-C104780
Western Blot (non-reducing) of IL1B / IL-1 Beta antibody LS-C104781.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of IL1B / IL-1 Beta antibody LS-C104781.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Rat IL-1B / IL-1 Beta
Rat
ELISA Neut WB
Biotin Conjugated
IL-1B / IL-1 Beta Antibody (clone ID4) LS-C7715

Mouse Monoclonal [clone ID4] (IgG1) to Sheep IL-1B / IL-1 Beta
Goat, Sheep, Bovine
ELISA Flo IHC IHC-Fr
Unconjugated
IL-1B / IL-1 Beta Antibody LS-C104813
Western Blot (non-reducing) of IL1B / IL-1 Beta antibody LS-C104813.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of IL1B / IL-1 Beta antibody LS-C104813.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Mouse IL-1B / IL-1 Beta
Mouse
ELISA Neut WB
Unconjugated
IL-1B / IL-1 Beta Antibody LS-C48792

Rabbit Polyclonal to Mouse IL-1B / IL-1 Beta
Mouse
ELISA Neut WB
Unconjugated
IL-1B / IL-1 Beta Antibody (clone 11n92, PE) LS-C184791

Rat Monoclonal [clone 11n92] (IgG2b) to Mouse IL-1B / IL-1 Beta
Mouse
Flo
PE Conjugated
IL-1B / IL-1 Beta Antibody (clone CRM56) LS-C107088
Human peripheral blood mononuclear cells were stimulated with LPS in the presence of Brefeldin A for 4 hours. The cells were surface stained with FITC anti-human CD14 and intracellularly stained with PE anti-human IL-1b.

Mouse Monoclonal [clone CRM56] (IgG1) to Human IL-1B / IL-1 Beta
Human
ELISA Flo Neut
Unconjugated
IL-1B / IL-1 Beta Antibody (Azide-free) LS-C44741

Mouse Monoclonal (IgG1) to Pig IL-1B / IL-1 Beta
Pig
WB
Unconjugated, Azide-free
IL-1B / IL-1 Beta Antibody (aa118-268) LS-C294792
Western blot of recombinant IL1B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Guinea pig Polyclonal (IgG) to Rabbit IL-1B / IL-1 Beta
Rabbit
WB
Unconjugated
IL-1B / IL-1 Beta Antibody (aa148-174, APC) LS-C278482

Rabbit Polyclonal (IgG) to Human IL-1B / IL-1 Beta
Human
ELISA Flo IHC WB
APC Conjugated
IL-1B / IL-1 Beta Antibody (N-Terminus) LS-C59377

Rabbit Polyclonal to Human IL-1B / IL-1 Beta
Dog, Human, Primate
ELISA IHC IHC-Fr IHC-P IP WB
Unconjugated
IL-1B / IL-1 Beta Antibody (Biotin) LS-C196050

Goat Polyclonal (IgG) to Human IL-1B / IL-1 Beta
Human
ELISA IHC WB
Biotin Conjugated
IL-1B / IL-1 Beta Antibody LS-C7736

Mouse Monoclonal (IgG1,k) to Human IL-1B / IL-1 Beta
Human
ELISA WB
Unconjugated
IL-1B / IL-1 Beta Antibody LS-C70853

Mouse Monoclonal (IgG1) to Human IL-1B / IL-1 Beta
Mouse, Human
ELISA WB
Unconjugated
IL-1B / IL-1 Beta Antibody LS-C7708

Goat Polyclonal (IgG) to Human IL-1B / IL-1 Beta
Human
ELISA Neut WB
Unconjugated
IL-1B / IL-1 Beta Antibody (Azide-free) LS-C130138

Rabbit Polyclonal (IgG) to Chicken IL-1B / IL-1 Beta
Chicken
ELISA Func WB
Unconjugated, Azide-free
IL-1B / IL-1 Beta Antibody (clone 1400.24) LS-C96389

Mouse Monoclonal [clone 1400.24]
Mouse
ELISA
Unconjugated
IL-1B / IL-1 Beta Antibody (clone 43N3D8) LS-C359459
Immunohistochemistry-Paraffin: IL1 beta Antibody (43N3D8) - analysis of Interleukin-1 beta in human kidney tissue using Interleukin-1 beta antibody at 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: IL1 beta Antibody (43N3D8) - Western blot analysis of full length human IL-1 beta recombinant protein (10ng/well) using IL1 beta Antibody at 1:1000 (left lane) and 1:100 (right lane).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Mouse Monoclonal [clone 43N3D8] to Human IL-1B / IL-1 Beta
Human
Flo IHC IHC-P WB
Unconjugated

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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