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IKZF2 / HELIOS
IKAROS family zinc finger 2 (Helios)
IKZF2 / HELIOS is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
| Gene Name: | IKAROS family zinc finger 2 (Helios) |
| Synonyms: | IKZF2, ANF1A2, HELIOS, Zinc finger protein Helios, ZNF1A2, ZNFN1A2 |
| Target Sequences: | NM_016260 NP_057344.2 Q9UKS7 |
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