IK3-1 / CABLES1

Cdk5 and Abl enzyme substrate 1

Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

IK3-1 / CABLES1 (4)

Publications

No (4)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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IK3-1 / CABLES1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107351

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.7 kDa

Price:

100 µg/$494

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Human IK3-1 / CABLES1 Protein (Recombinant His, N-Terminal) - LS-G144437

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

41.7 kDa

Price:

50 µg/$419

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Human IK3-1 / CABLES1 Protein (Recombinant GST) (Full Length) - LS-G36038

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IK3-1 / CABLES1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84982

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.7 kDa

Price:

20 µg/$150

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