IgG1 Fc

The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. In IgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and a-2,6 linked sialic acid residues.

IgG1 Fc Target Details

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Products

Antibodies (5)

Proteins (4)

Type

Primary (5)

Recombinant (4)

Target

IgG1 Fc (9)

Reactivity

Human (5)

Application

IHC (5)

ELISA (5)

Host

mouse (5)

Isotype

IgG2a (5)

Clonality

monoclonal mc (5)

Format

AP Conjugated (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Publications

No (9)

Tag

AVI, C-terminus (1)

Human IgG1 Fc (1)

Species

Human (4)

Source

CHO Cells (1)

HEK 293 Cells (2)

Human (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (4)

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Human IgG1 Fc Protein (Recombinant) (aa100-330) - LS-G4051

Source:

HEK 293 Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$442

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IgG1 Fc Antibody (HRP) LS-C546946

Antibody:

IgG1 Fc Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated

Price:

100 µl/$920

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IgG1 Fc Antibody (Biotin) LS-C526837

Antibody:

IgG1 Fc Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

100 µl/$920

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IgG1 Fc Antibody (FITC) LS-C536819

Antibody:

IgG1 Fc Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

100 µl/$920

Select

IgG1 Fc Antibody (PE) LS-C654999

Antibody:

IgG1 Fc Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

100 µl/$920

Select

IgG1 Fc Antibody (AP) LS-C508829

Antibody:

IgG1 Fc Mouse anti-Human Monoclonal (AP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

AP Conjugated

Price:

100 µl/$920

• HRP
• Biotin
• FITC
• PE
• AP

• HRP
• Biotin
• FITC
• More...
  • PE
  • AP

Select

Human IgG1 Fc Protein (Recombinant) (aa100-330) - LS-G4088

Source:

HEK 293 Cells

Tag:

None

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$442

Select

Human IgG1 Fc Protein (Recombinant AVI, C-terminus) - LS-G146168

Source:

Human

Tag:

AVI, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

27.7 kDa

Price:

20 µg/$416; 100 µg/$910

Select

Human IgG1 Fc Protein (Recombinant Human IgG1 Fc) (aa105-330) - LS-G4160

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

~28kDa (SDS-PAGE)

Price:

50 µg/$309

Viewing 1-9 of 9 product results

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