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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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IGF2BP2
Insulin-like growth factor 2 mRNA binding protein 2
RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.
| Gene Name: | Insulin-like growth factor 2 mRNA binding protein 2 |
| Synonyms: | IGF2BP2, IMP2, IGF2 mRNA-binding protein 2, p62, VICKZ2, IGF-II mRNA-binding protein 2, IMP-2, VICKZ family member 2 |
| Target Sequences: | NM_006548 NP_006539.3 Q9Y6M1 |
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