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IFT74 / CCDC2

intraflagellar transport 74 homolog (Chlamydomonas)

Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.

Gene Name: intraflagellar transport 74 homolog (Chlamydomonas)
Synonyms: IFT74, CCDC2, CMG-1, CMG1
Target Sequences: NM_025103 NP_079379.2 Q96LB3

Publications (2)

1
Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. Momeni P, Schymick J, Jain S, Cookson MR, Cairns NJ, Greggio E, Greenway MJ, Berger S, Pickering-Brown S, Chi A, Fung HC, Holtzman DM, Huey ED, Wassermann EM, Adamson J, Hutton ML, Rogaeva E, St George-Hyslop P, Rothstein JD, Hardiman O, Grafman J, Single. BMC neurology. 2006 6:44. [PubMed:17166276] [PMC:PMC1764752] Related Antibodies: LS-B2293.
2
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice. Boldt K, Mans DA, Won J, van Reeuwijk J, Vogt A, Kinkl N, Letteboer SJ, Hicks WL, Hurd RE, Naggert JK, Texier Y, den Hollander AI, Koenekoop RK, Bennett J, Cremers FP, Gloeckner CJ, Nishina PM, Roepman R, Ueffing M. The Journal of clinical investigation. 2011 121:2169-80. [PubMed:21606596] [PMC:PMC3104757] Related Antibodies: LS-B2293.

☰ Filters
Products
Antibodies (16)
Primary (16)
IFT74 / CCDC2 (16)
Human (15)
Mouse (3)
Rat (6)
Bovine (3)
Chimpanzee (6)
Dog (3)
Guinea pig (3)
Horse (6)
Monkey (1)
Orangutan (3)
Rabbit (3)
IHC (2)
IHC-P (1)
WB (15)
ELISA (2)
ICC (1)
Peptide-ELISA (2)
rabbit (14)
goat (2)
Product Group
IHCPlus (1)
IgG (6)
polyclonal pc (16)
Biotin Conjugated (3)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (9)
C-Terminus (4)
aa221-270 (4)
C Terminus (1)
aa538-600 (1)
aa588-600 (1)
No (15)
Yes (1)
IFT74 / CCDC2 Antibody - Anti-IFT74 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IFT74 / CCDC2 Goat anti-Human Polyclonal (aa588-600) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
IFT74 / CCDC2 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using IFT74 Polyclonal Antibody at dilution of 1:60.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IFT74 / CCDC2 Antibody - Immunofluorescence of methanol-fixed A431 using CMG1 antibody at 1:500 dilution.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal (aa538-600) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
IFT74 / CCDC2 Antibody - Western blot analysis of HepG2 and 293T cell, using IFT74 Polyclonal Antibody at dilution of 1:1400.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
IFT74 / CCDC2 Antibody - IFT74 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
IFT74 / CCDC2 Antibody - IFT74 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Horse, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
IFT74 / CCDC2 Antibody - IFT74 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Horse, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
IFT74 / CCDC2 Antibody - IFT74 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Horse, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
IFT74 / CCDC2 Antibody - Western blot analysis of extracts of various cell lines, using IFT74 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IFT74 / CCDC2 Antibody - Western blot analysis of extracts of various cell lines, using IFT74 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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IFT74 / CCDC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IFT74 / CCDC2 Antibody - IFT74 / CCDC2 biotinylated antibody (0.2µg/ml) staining of HEK293 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a substitue for skimmed milk.
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IFT74 / CCDC2 Goat anti-Human Polyclonal (C Terminus) (Biotin) Antibody
Human
Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
IFT74 / CCDC2 Antibody - Western blot of Rat Lung . Ift74 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IFT74 / CCDC2 Rabbit anti-Rat Polyclonal (aa221-270) Antibody
Rat
WB
Unconjugated
100 µl/$424
IFT74 / CCDC2 Antibody - Western blot of Rat Lung . Ift74 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IFT74 / CCDC2 Rabbit anti-Rat Polyclonal (aa221-270) (HRP) Antibody
Rat, Horse, Orangutan, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
IFT74 / CCDC2 Antibody - Western blot of Rat Lung . Ift74 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IFT74 / CCDC2 Rabbit anti-Rat Polyclonal (aa221-270) (Biotin) Antibody
Rat, Horse, Orangutan, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
IFT74 / CCDC2 Antibody - Western blot of Rat Lung . Ift74 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IFT74 / CCDC2 Rabbit anti-Rat Polyclonal (aa221-270) (FITC) Antibody
Rat, Horse, Orangutan, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).