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IFNGR2

interferon gamma receptor 2 (interferon gamma transducer 1)

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

Gene Name: interferon gamma receptor 2 (interferon gamma transducer 1)
Family/Subfamily: Interferon Receptor , not assigned-Interferon Receptor
Synonyms: IFNGR2, AF-1, IFN-gamma receptor 2, IFGR2, IFNGT1, Interferon gamma receptor 2, Interferon gamma transducer 1, IFN-gamma-R2
Target Sequences: NM_005534 NP_005525.2 P38484

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).