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IFNAR1 / IFNAR
interferon (alpha, beta and omega) receptor 1
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
| Gene Name: | interferon (alpha, beta and omega) receptor 1 |
| Family/Subfamily: | Interferon Receptor , not assigned-Interferon Receptor |
| Synonyms: | IFNAR1, Alpha-type antiviral protein, Beta-type antiviral protein, CRF2-1, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFN-R-1, IFNAR, IFNBR, IFRC, Interferon-beta receptor 1, Interferon-alpha receptor, Type I interferon receptor 1 |
| Target Sequences: | NM_000629 NP_000620.2 P17181 |
Publications (1)
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