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IFN Gamma / Interferon Gamma

interferon, gamma

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

Gene Name: interferon, gamma
Family/Subfamily: Interferon , not assigned-Interferon
Synonyms: IFNG, IFG, Immune interferon, IFI, Interferon gamma, IFN-gamma, Interferon, gamma, IFNY
Target Sequences: NM_000619 NP_000610.2 P01579

Publications (4)

1
TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, Masunaga A, Ogawa Y, Oguchi K, Miyazaki A. Journal of immunology (Baltimore, Md. : 1950). 2007 179:1449-57. [PubMed:17641010] Related Antibodies: LS-C41022.
2
Retinoid-X-receptors (a/ß) in melanocytes modulate innate immune responses and differentially regulate cell survival following UV irradiation. Coleman DJ, Garcia G, Hyter S, Jang HS, Chagani S, Liang X, Larue L, Ganguli-Indra G, Indra AK. PLoS genetics. 2014 10:e1004321. (Neut; Mouse) [Full Text Article] [PubMed:24810760] [PMC:PMC4014444] Related Antibodies: LS-C85867.
3
Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model. Liu WC, Nachbagauer R, Stadlbauer D, Solórzano A, Berlanda-Scorza F, García-Sastre A, Palese P, Krammer F, Albrecht RA. Frontiers in immunology. 2019 April;10: [Full Text Article] [PubMed:31105689] [PMC:PMC6499175] Related Antibodies: LS-C188182.
4
High Levels of IL-18 and IFN-? in Chronically Inflamed Tissue in Chronic Granulomatous Disease. Meda Spaccamela V, Valencia RG, Pastukhov O, Duppenthaler A, Dettmer MS, Erb J, Steiner UC, Hillinger S, Speckmann C, Ehl S, Reichenbach J, Siler U. Frontiers in immunology. 2019 October;10: [Full Text Article] [PubMed:31681257] [PMC:PMC6813411] Related Antibodies: LS-B7487.
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Proteins (82)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (77)
IFN Gamma / Interferon Gamma (82)
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Coronavirus Antibodies Proteins cDNAs (81)
Cytokine Release Syndrome (82)
Cytokine Release Syndrome Proteins (81)
Animal-free (2)
No (82)
6His, C-terminus (2)
6His, N-terminus (4)
Fc, C-terminus (1)
GST (2)
GST, N-terminus (1)
His (13)
His, N-Terminal (12)
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IFN Gamma / Interferon Gamma Protein
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.9kDa
100 µg/$317; 500 µg/$526; 20 µg/$245; 50 µg/$273; 250 µg/$429
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
20 µg/$282; 100 µg/$369
IFN Gamma / Interferon Gamma Protein - Eukaryotic Interferon Gamma (IFNg) by SDS-PAGE
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293F Cells
His, N-Terminal
22-27kDa
10 µg/$331; 50 µg/$752; 200 µg/$1,365; 100 µg/$1,156; 1 mg/$2,648; 500 µg/$2,144; 5 mg/$5,251; 2 mg/$2,838
IFN Gamma / Interferon Gamma Protein - Recombinant Interferon Gamma By SDS-PAGE
Select
E. coli
His
18.3 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
IFN Gamma / Interferon Gamma Protein - Recombinant Rabbit interferon gamma detected using Goat anti Rabbit interferon gamma as the capture reagent and Goat anti Rabbit interferon gamma:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
16.9 kDa
5 µg/$390
IFN Gamma / Interferon Gamma Protein - Recombinant  Interferon Gamma By SDS-PAGE
Select
E. coli
His-T7
20.7 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
IFN Gamma / Interferon Gamma Protein
Select
E. coli
None
Biologically active
16.8 kDa
10 µg/$282; 500 µg/$946; 100 µg/$468
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
20 µg/$281; 100 µg/$369
IFN Gamma / Interferon Gamma Protein - Recombinant Interferon Gamma By SDS-PAGE
Select
E. coli
His
18.7 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
IFN Gamma / Interferon Gamma Protein - N.A.
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~17 kDa
100 µg/$291; 1 mg/$746
Select
E. coli
His,C-terminus
Less than 0.1 EU/µg protein (determined by LAL method).
~17 kDa (SDS-PAGE)
10 µg/$288; 50 µg/$428
IFN Gamma / Interferon Gamma Protein - Eukaryotic Interferon Gamma (IFNg) by SDS-PAGE
Select
293F Cells
His, N-Terminal
22/25kDa
10 µg/$318; 50 µg/$672; 200 µg/$1,256; 100 µg/$1,057; 1 mg/$2,507; 500 µg/$2,007; 5 mg/$4,691; 2 mg/$2,699
IFN Gamma / Interferon Gamma Protein - Recombinant Dog Interferon gamma detected using Rabbit anti Dog interferon gamma as the capture reagent and Rabbit anti Dog Interferon gamma:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
16.7 kDa
5 µg/$390
IFN Gamma / Interferon Gamma Protein - Recombinant Pig Interferon gamma detected using Rabbit anti Pig interferon gamma as the capture reagent and Rabbit anti Pig Interferon gamma:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
16.8 kDa
5 µg/$390
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).
The 134 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 15,652 Da. The DTT-reduced and non-reduced protein migrate at approximately 13 kD by SDS-PAGE.
10 µg/$246; 25 µg/$283; 100 µg/$359; 500 µg/$749
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).
The 144 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 16,907 Da. The DTT-reduced protein and the non-reduced protein migrate at approximately 17 kDa by SDS-PAGE.
10 µg/$264; 25 µg/$306; 100 µg/$359; 500 µg/$749
IFN Gamma / Interferon Gamma Protein - Active Interferon Gamma (IFNg) by WB
Select
E. coli
His, N-Terminal
18kDa
10 µg/$352; 50 µg/$877; 200 µg/$1,523; 100 µg/$1,298; 1 mg/$2,838; 500 µg/$2,334; 5 mg/$6,125; 2 mg/$3,268
Select
CHO Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.7 kDa
20 µg/$287; 100 µg/$390
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
42.5 kDa
100 µg/$661
Select
Mammalian Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
16.8 kDa
10 µg/$248; 50 µg/$317
Select
CHO Cells
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$325; 1 mg/$1,195; 20 µg/$255
IFN Gamma / Interferon Gamma Protein
Select
E. coli
His, N-Terminal
16.7 kDa
50 µg/$419
Select
E. coli
His
21 kD
20 µg/$405; 1 mg/$1,679; 100 µg/$598
IFN Gamma / Interferon Gamma Protein - 12.5% SDS-PAGE of human IFNG stained with Coomassie Blue
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Wheat Germ Extract
GST
43.89 kDa
2 µg/$439
Select
HEK 293 Cells
His
17.1 kDa
10 µg/$315; 50 µg/$522; 100 µg/$782
Viewing 26-50 of 82 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).