IFIX / PYHIN1

pyrin and HIN domain family, member 1

IFIX / PYHIN1 belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

IFIX / PYHIN1 (5)

Publications

No (5)

Tag

GST (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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IFIX / PYHIN1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106232

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.9 kDa

Price:

100 µg/$710

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Human IFIX / PYHIN1 Protein (Recombinant GST) (Full Length) - LS-G36711

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

78.3 kDa

Price:

2 µg/$439

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Human IFIX / PYHIN1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93397

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.9 kDa

Price:

20 µg/$215

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Human IFIX / PYHIN1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93399

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.8 kDa

Price:

20 µg/$215

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IFIX / PYHIN1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103421

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.8 kDa

Price:

100 µg/$710

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