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IFITM2

interferon induced transmembrane protein 2

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Gene Name: interferon induced transmembrane protein 2
Synonyms: IFITM2, 1-8D, Dispanin subfamily A member 2c, DSPA2c
Target Sequences: NM_006435 NP_006426.2 Q01629

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
IFITM2 (6)
No (6)
GST (2)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Purified (2)
IFITM2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
IFITM2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
14.5 kDa
20 µg/$150
IFITM2 Protein - 12.5% SDS-PAGE of human IFITM2 stained with Coomassie Blue
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Wheat Germ Extract
GST
40.26 kDa
10 µg/$479; 25 µg/$670
IFITM2 Protein - 12.5% SDS-PAGE of human IFITM2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
41 kDa
10 µg/$479; 25 µg/$670
IFITM2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
14.5 kDa
100 µg/$494
IFITM2 Protein
Select
E. coli
GST, N-terminus + His, C-terminus
42.5 kDa
50 µg/$419
Viewing 1-6 of 6 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).