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IFIT5

interferon-induced protein with tetratricopeptide repeats 5

Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

Gene Name: interferon-induced protein with tetratricopeptide repeats 5
Synonyms: IFIT5, IFIT-5, p58, RI58
Target Sequences: NM_012420 NP_036552.1 Q13325

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
IFIT5 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
IFIT5 Protein - 12.5% SDS-PAGE of human IFIT5 stained with Coomassie Blue
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Wheat Germ Extract
GST
78.76 kDa
10 µg/$479; 25 µg/$670
IFIT5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.7 kDa
100 µg/$494
IFIT5 Protein - Purified recombinant protein IFIT5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.7 kDa
20 µg/$1,107
IFIT5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.7 kDa
20 µg/$150
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).