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IFIT1 / ISG56

interferon-induced protein with tetratricopeptide repeats 1

Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

Gene Name: interferon-induced protein with tetratricopeptide repeats 1
Synonyms: IFIT1, C56, G10P1, GARG-16, IFI-56K, IFIT-1, Interferon-inducible mRNA 561, IFI-56, IFI56, IFNAI1, ISG56, RNM561, p56
Target Sequences: NM_001270927 NP_001257856.1

☰ Filters
Products
ELISA Kits (4)
Custom (1)
Sandwich (3)
IFIT1 / ISG56 (4)
Human (3)
Mouse (1)
96-Well Strip Plate (4)
No (4)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (3)
IFIT1 / ISG56 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
IFIT1 / ISG56 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
IFIT1 / ISG56 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
IFIT1 / ISG56 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Viewing 1-4 of 4 product results


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Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).