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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IDH3B

Isocitrate Dehydrogenase 3 (NAD+) Beta

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: Isocitrate Dehydrogenase 3 (NAD+) Beta
Synonyms: IDH3B, H-IDHB, RP46, NAD+-specific ICDH
Target Sequences: NM_006899 NP_008830.2 O43837

Filtered By: None
Target
IDH3B (34)
Reactivity
Human (34)
Mouse (15)
Rat (14)
Bat (4)
Bovine (13)
Chimpanzee (6)
Dog (4)
Gibbon (6)
Guinea pig (8)
Horse (9)
Monkey (9)
Orangutan (3)
Pig (9)
Rabbit (8)
Xenopus (4)
Application
IHC (8)
IHC-P (5)
WB (33)
ELISA (8)
Peptide-ELISA (3)
Host
rabbit (31)
mouse (1)
goat (2)
Isotype
IgG (15)
IgG3,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (33)
Clone
3A10 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (1)
Unconjugated (16)
Epitope
C-Terminus (4)
aa44-93 (4)
aa86-135 (4)
Internal (1)
aa15-49 (1)
aa33-46 (1)
aa369-383 (1)
aa51-100 (1)
aa90-378 (1)
Publications
No (34)
Showing 1-25 of 34 results

IDH3B Antibody IHC-plus™ LS-B13001
Rabbit Polyclonal (IgG) to Human IDH3B
Mouse, Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (HRP) LS-C317366
Rabbit Polyclonal (IgG) to Human IDH3B
Human
ELISA IHC IHC-P WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (Biotin) LS-C317364
Rabbit Polyclonal (IgG) to Human IDH3B
Human
ELISA IHC IHC-P WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (FITC) LS-C317365
Rabbit Polyclonal (IgG) to Human IDH3B
Human
ELISA IHC IHC-P WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (aa90-378) LS-C178571
Rabbit Polyclonal to Human IDH3B
Human
ELISA IHC WB
Unconjugated
100µg 1mg/ml  $255.00
Immunohistochemistry Image
Western blot Image
Immunohistochemistry Image
Western blot Image

IDH3B Antibody LS-C401308
Rabbit Polyclonal (IgG) to Human IDH3B
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using IDH3B Polyclonal Antibody at dilution of 1:30.
Western blot analysis of HepG2 cell and mouse kidney tissue, LOVO cell and mouse eyes tissue, HeLa cell, using IDH3B Polyclonal Antibody at dilution of 1:233.3.
Immunohistochemistry of Human thyroid cancer using IDH3B Polyclonal Antibody at dilution of 1:30.
Western blot analysis of HepG2 cell and mouse kidney tissue, LOVO cell and mouse eyes tissue, HeLa cell, using IDH3B Polyclonal Antibody at dilution of 1:233.3.

IDH3B Antibody LS-C404584
Rabbit Polyclonal (IgG) to Human IDH3B
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using IDH3B Polyclonal Antibody at dilution of 1:30.
Western blot analysis of Mouse eyes tissue, using IDH3B Polyclonal Antibody at dilution of 1:240.
Immunohistochemistry of Human thyroid cancer using IDH3B Polyclonal Antibody at dilution of 1:30.
Western blot analysis of Mouse eyes tissue, using IDH3B Polyclonal Antibody at dilution of 1:240.

IDH3B Antibody (aa15-49) LS-C344217
Rabbit Polyclonal to Human IDH3B
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
Immunohistochemical of paraffin-embedded H.brain section using IDH3B Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Western blot of lysates from HeLa cell line and human placenta tissue lysate (from left to right) with IDH3B Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.
Immunohistochemical of paraffin-embedded H.brain section using IDH3B Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
Western blot of lysates from HeLa cell line and human placenta tissue lysate (from left to right) with IDH3B Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

IDH3B Antibody (aa51-100) LS-C199894
Rabbit Polyclonal (IgG) to Human IDH3B
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from Jurkat cells, using IDH3B antibody.
Western blot analysis of lysates from Jurkat cells, using IDH3B antibody.

IDH3B Antibody (clone 3A10) LS-C197487
Mouse Monoclonal [clone 3A10] (IgG3,k) to Human IDH3B
Human
ELISA
Unconjugated
100µg  $355.00

IDH3B Antibody (aa369-383) LS-C154850
Goat Polyclonal to Human IDH3B
Mouse, Human
Peptide-ELISA WB
Unconjugated
100µg 0.5mg/ml  $405.00
IDH3B antibody (0.03 ug/ml) staining of Mouse fetal Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
IDH3B antibody (0.03 ug/ml) staining of Mouse fetal Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IDH3B Antibody (aa33-46) LS-C139804
Goat Polyclonal to Human IDH3B
Horse, Human
Peptide-ELISA WB
Unconjugated
100µg  $405.00
IDH3B antibody (0.3 ug/ml) staining of Human Skeletal muscle lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
IDH3B antibody (0.3 ug/ml) staining of Human Skeletal muscle lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IDH3B Antibody LS-C310685
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
Unconjugated
100µg  $605.00

IDH3B Antibody (HRP) LS-C542626
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
HRP Conjugated
100µl  $755.00

IDH3B Antibody (Biotin) LS-C522496
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
Biotin Conjugated
100µl  $755.00

IDH3B Antibody (FITC) LS-C532540
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
FITC Conjugated
100µl  $755.00

IDH3B Antibody (AP) LS-C504572
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
AP Conjugated
100µl  $755.00

IDH3B Antibody (APC) LS-C514281
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
APC Conjugated
100µl  $755.00

IDH3B Antibody (PE) LS-C650740
Rabbit Polyclonal (IgG) to Human IDH3B
Human
WB
PE Conjugated
100µl  $755.00

IDH3B Antibody (aa86-135) LS-C152201
Rabbit Polyclonal to Human IDH3B
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
IDH3B antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IDH3B antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (aa44-93) LS-C205859
Rabbit Polyclonal to Human IDH3B
Bovine, Human
WB
Unconjugated
50µg  $365.00
IDH3B antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IDH3B antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (C-Terminus) LS-C201634
Rabbit Polyclonal to Human IDH3B
Xenopus, Rat, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Monkey
WB
Unconjugated
50µg  $365.00
Western blot of Human THP-1. IDH3B antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human THP-1. IDH3B antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IDH3B Antibody (Internal) LS-C354394
Rabbit Polyclonal to Human IDH3B
Mouse, Bovine, Rat, Pig, Human, Monkey
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of IDH3 beta expression in HeLa (A); Jurkat (B); PC12 (C) whole cell lysates.
Western blot analysis of IDH3 beta expression in HeLa (A); Jurkat (B); PC12 (C) whole cell lysates.

IDH3B Antibody LS-C411790
Rabbit Polyclonal to Human IDH3B
Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot of IDH3B antibody at 1:500 dilution. Lane 1: HeLa whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: PC12 whole cell lysate.
Western blot of IDH3B antibody at 1:500 dilution. Lane 1: HeLa whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: PC12 whole cell lysate.

IDH3B Antibody LS-C748773
Rabbit Polyclonal (IgG) to Human IDH3B
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of various cell lines, using IDH3B antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Western blot analysis of extracts of various cell lines, using IDH3B antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Showing 1-25 of 34 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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