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Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.
Gene Name: | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
Synonyms: | ID4, BHLHb27, IDB4, Inhibitor of DNA binding 4 |
Target Sequences: | NM_001546 NP_001537.1 P47928 |
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