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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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ICAM3 / CD50
intercellular adhesion molecule 3
ICAM3 / CD50 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
| Gene Name: | intercellular adhesion molecule 3 |
| Family/Subfamily: | ICAM , not assigned-ICAM |
| Synonyms: | ICAM3, CD50, CDW50, ICAM-R, CD50 antigen, ICAM-3 |
| Target Sequences: | NM_002162 NP_002153.2 P32942 |
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