Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

IBSP / Bone Sialoprotein

integrin-binding sialoprotein

IBSP / Bone Sialoprotein is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.

Gene Name: integrin-binding sialoprotein
Synonyms: IBSP, Bone Sialoprotein, Bone sialoprotein II, BSP, BSP II, Cell-binding sialoprotein, BNSP, Bone Sialprotein II, Integrin-binding sialoprotein, Bone sialoprotein 2, BSP-II, SP-II
Target Sequences: NM_004967 NP_004958.2 P21815

Publications (2)

1
BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts. Yuhei Yahiro #, Shingo Maeda #, Masato Morikawa, Daizo Koinuma, Go Jokoji, Toshiro Ijuin, Setsuro Komiya, Ryoichiro Kageyama, Kohei Miyazono, Noboru Taniguchi. Bone research. 2020 September;8:32. [Full Text Article] [PubMed:32923015] [PMC:PMC7463266] Related Antibodies: LS-C190916.
2
Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S. The Journal of biological chemistry. 2014 Apr;289:9865-79. [Full Text Article] [PubMed:24563464] [PMC:PMC3975031] Related Antibodies: LS-C190916.

☰ Filters
Products
ELISA Kits (17)
Competitive EIA (1)
Custom (5)
Sandwich (9)
Sandwich CLIA (2)
IBSP / Bone Sialoprotein (17)
Human (4)
Mouse (4)
Rat (5)
Chicken (1)
Monkey (1)
Pig (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (3)
96-Well Strip Plate (13)
No (17)
Plasma (11)
Serum (11)
Tissue Homogenates (4)
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IBSP / Bone Sialoprotein ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
IBSP / Bone Sialoprotein ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
IBSP / Bone Sialoprotein ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
IBSP / Bone Sialoprotein ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
IBSP / Bone Sialoprotein ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
IBSP / Bone Sialoprotein ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
125 - 8000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
IBSP / Bone Sialoprotein ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Viewing 1-17 of 17 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).