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I-309 / CCL1
chemokine (C-C motif) ligand 1
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
| Gene Name: | chemokine (C-C motif) ligand 1 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL1, C-C motif chemokine 1, I-309, p500, Inflammatory cytokine I-309, TCA3, SISe, Small-inducible cytokine A1, Chemokine (C-C motif) ligand 1, SCYA1 |
| Target Sequences: | NM_002981 NP_002972.1 P22362 |
Publications (1)
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