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Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.
Gene Name: | Huntingtin Interacting Protein K |
Synonyms: | HYPK, HSPC136, C15orf63 |
Target Sequences: | NM_016400 NP_057484.3 Q9NX55 |
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