HYAL2

hyaluronoglucosaminidase 2

HYAL2 is a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

HYAL2 (7)

Publications

No (7)

Tag

GST, N-terminus (1)

His (2)

Myc-DDK (Flag) (4)

Species

Human (4)

Mouse (1)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

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Human HYAL2 Protein (Recombinant GST, N-terminus) (aa340-439) - LS-G60827

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HYAL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81434

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

20 µg/$150

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Human HYAL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81436

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

20 µg/$150

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Mouse HYAL2 Protein (Recombinant His) (aa23-447) - LS-G15441

Source:

E. coli

Tag:

His

Molecular Weight:

50.2 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human HYAL2 Protein (Recombinant His) (aa21-448) - LS-G23380

Source:

Yeast

Tag:

His

Molecular Weight:

51.3 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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HYAL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100126

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

100 µg/$494

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HYAL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102114

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.7 kDa

Price:

100 µg/$494

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