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HVCN1 / HV1

Hydrogen voltage-gated channel 1

This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Hydrogen voltage-gated channel 1
Synonyms: HVCN1, HV1, VSOP
Target Sequences: NM_032369 NP_115745.2 Q96D96

Publications (2)

1
Respiratory syncytial virus infection of microglia exacerbates SH-SY5Y neuronal cell injury by inducing the secretion of inflammatory cytokines: A Transwell in vitro study. Xiao-Yan Zhang, Xiao-Cheng Zhang, Hai-Yang Yu, Yun Wang, Jason Chen, Yang Wang, Li Yu, Guo-Xin Zhu, Xiu-Jing Cao, Sheng-Hai Huang. Iranian journal of basic medical sciences. 2021 February;24:213-221. [Full Text Article] [PubMed:33953861] [PMC:PMC8061319] Related Antibodies: LS-C675877.
2
HVCN1 Channels Are Relevant for the Maintenance of Sperm Motility During In Vitro Capacitation of Pig Spermatozoa. Marc Yeste, Marc Llavanera, Yentel Mateo-Otero, Jaime Catalán, Sergi Bonet, Elisabeth Pinart. International journal of molecular sciences. 2020 May;21:3255. [Full Text Article] [PubMed:32375375] [PMC:PMC7246839] Related Antibodies: LS-C146080.

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Products
Antibodies (19)
Primary (19)
HVCN1 / HV1 (19)
Human (18)
Mouse (6)
Rat (5)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Horse (3)
Pig (3)
Rabbit (3)
IHC (7)
IHC-P (3)
WB (19)
Flo (7)
ELISA (9)
IF (1)
rabbit (17)
rabbit-new zealand white (2)
Product Group
IHCPlus (2)
IgG (11)
polyclonal pc (19)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
aa1-30 (7)
C-Terminus (4)
N-Terminus (1)
No (17)
Yes (2)
HVCN1 / HV1 Antibody - Anti-HVCN1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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HVCN1 / HV1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
HVCN1 / HV1 Antibody - RGD1310788 antibody Western blot of Rat Muscle lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HVCN1 / HV1 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat, Human
WB
Unconjugated
100 µl/$424
HVCN1 / HV1 Antibody - RGD1310788 antibody Western blot of Rat Muscle lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HVCN1 / HV1 Rabbit anti-Rat Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
HVCN1 / HV1 Antibody - RGD1310788 antibody Western blot of Rat Muscle lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HVCN1 / HV1 Rabbit anti-Rat Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
HVCN1 / HV1 Antibody - RGD1310788 antibody Western blot of Rat Muscle lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HVCN1 / HV1 Rabbit anti-Rat Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
HVCN1 / HV1 Antibody - Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100
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HVCN1 / HV1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
HVCN1 / HV1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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HVCN1 / HV1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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HVCN1 / HV1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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HVCN1 / HV1 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
HVCN1 / HV1 Antibody - Western blot of HVCN1 Antibody in Jurkat cell line lysates (35 ug/lane). HVCN1 (arrow) was detected using the purified antibody.
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HVCN1 / HV1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
Select
HVCN1 / HV1 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
HVCN1 / HV1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-19 of 19 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).