HUS1

HUS1 checkpoint homolog (S. pombe)

Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.

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Products

Antibodies (29)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (29)

Recombinant (4)

Target

HUS1 (35)

Reactivity

Human (29)

Mouse (6)

Rat (3)

Application

IHC (8)

IHC-P (1)

WB (26)

ELISA (15)

IF (2)

IP (3)

Peptide-ELISA (1)

Host

rabbit (27)

mouse (2)

Isotype

IgG (26)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (28)

Clone

2B12 (1)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (16)

Epitope

aa199-226 (7)

aa1-273 (1)

Publications

No (34)

Yes (1)

Tag

GST (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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HUS1 Antibody LS-C308354

(4.0) Rating

(1) Publication(s)

Antibody:

HUS1 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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HUS1 Antibody LS-C334043

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HUS1 Antibody LS-C748954

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

HUS1 Antibody (aa1-273) LS-C186327

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa1-273) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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HUS1 Antibody LS-C666273

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

HUS1 Antibody LS-C317656

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

HUS1 Antibody (HRP) LS-C317663

Antibody:

HUS1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

HUS1 Antibody (Biotin) LS-C317651

Antibody:

HUS1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

HUS1 Antibody (FITC) LS-C317652

Antibody:

HUS1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

HUS1 Antibody LS-C806634

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

HUS1 Antibody LS-C767379

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HUS1 Antibody LS-C832099

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

HUS1 Antibody LS-C830598

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

HUS1 Antibody (aa199-226) LS-C322127

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

HUS1 Antibody (aa199-226, Biotin) LS-C215200

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

HUS1 Antibody (aa199-226, FITC) LS-C215201

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

HUS1 Antibody (aa199-226, APC) LS-C215199

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

HUS1 Antibody (aa199-226, Azide-free, HRP) LS-C215202

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

HUS1 Antibody (aa199-226, PE) LS-C215204

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

HUS1 Antibody LS-C779016

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

HUS1 Antibody (clone 2B12) LS-C197476

Antibody:

HUS1 Mouse anti-Human Monoclonal (2B12) Antibody

Reactivity:

Human

Applications:

ELISA, IP

Format:

Unconjugated

Price:

100 µg/$423

Select

HUS1 Antibody LS-C310672

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

Select

HUS1 Antibody LS-C310673

Antibody:

HUS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

HUS1 Antibody (APC) LS-C514267

Antibody:

HUS1 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• APC

• Unconjugated
• APC

Select

HUS1 Antibody (aa199-226) LS-C165090

Antibody:

HUS1 Rabbit anti-Human Polyclonal (aa199-226) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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