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HTS1 / ST5

suppression of tumorigenicity 5

Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.

Gene Name: suppression of tumorigenicity 5
Synonyms: ST5, DENN/MADD domain containing 2B, DENND2B, HeLa tumor suppression 1, HTS1, p126
Target Sequences: NM_005418 NP_005409.3 P78524

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Products
Antibodies (20)
Primary (20)
HTS1 / ST5 (20)
Human (20)
Mouse (5)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (4)
Pig (1)
Rabbit (4)
Sheep (1)
IHC (1)
IHC-P (1)
WB (18)
Flo (6)
ELISA (11)
IF (1)
Peptide-ELISA (3)
rabbit (19)
mouse (1)
Product Group
IHCPlus (1)
IgG (12)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (19)
1A3 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (12)
C-Terminus (6)
aa387-436 (4)
380-460 aa, Internal (1)
Internal (1)
aa1121-1137 (1)
aa388-437 (1)
aa411-460 (1)
aa571-586 (1)
No (20)
HTS1 / ST5 Antibody - Anti-ST5 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa1121-1137) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
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HTS1 / ST5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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HTS1 / ST5 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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HTS1 / ST5 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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HTS1 / ST5 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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HTS1 / ST5 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
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HTS1 / ST5 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
HTS1 / ST5 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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HTS1 / ST5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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HTS1 / ST5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
HTS1 / ST5 Antibody - Western blot analysis of extracts from COLO205 cells, using ST5 antibody.
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HTS1 / ST5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
HTS1 / ST5 Antibody - Western blot of ST5 antibody
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HTS1 / ST5 Rabbit anti-Human Polyclonal (380-460 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HTS1 / ST5 Antibody - Western blot analysis of lysates from COLO205 cells, using ST5 Antibody. The lane on the right is blocked with the synthesized peptide.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa411-460) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HTS1 / ST5 Antibody - Western blot analysis of the lysates from COLO205 cells using ST5 antibody.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa388-437) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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HTS1 / ST5 Mouse anti-Human Monoclonal (1A3) Antibody
Human
ELISA
Unconjugated
100 µg/$423
HTS1 / ST5 Antibody - ST5 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa387-436) Antibody
Human
WB
Unconjugated
100 µl/$424
HTS1 / ST5 Antibody - ST5 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa387-436) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
HTS1 / ST5 Antibody - ST5 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa387-436) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
HTS1 / ST5 Antibody - ST5 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa387-436) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
HTS1 / ST5 Antibody - WB of HTS1 / ST5 antibody. All lanes: Anti-ST5 at 0.5ug/ml. Lane 1: Rat Testis Tissue Lysate at 40ug. Lane 2: A431 Whole Cell Lysate at 40ug. Lane 3: HELA Whole Cell Lysate at 40ug. Lane 4: COLO320 Whole Cell Lysate at 40ug. Lane 5: NIH Whole Cell Lysate at 40ug. Predicted bind size: 126KD. Observed bind size: 126KD.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (aa571-586) Antibody
Rabbit, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
HTS1 / ST5 Antibody - Western blot analysis of ST5 expression in K562 (A); human spleen (B) whole cell lysates.
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HTS1 / ST5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
WB
Unconjugated
100 µl/$299
Viewing 1-20 of 20 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).