HTRA2 / OMI

HtrA serine peptidase 2

Inhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication. Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases. The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs. Recently, a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs. Similar to Smac, Omi possesses a conserved IAP-binding motif, but acts to cleave IAPs to irreversibly inactivate IAPs and promote apoptosis.

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Products

ELISA Kits (4)

Type

Custom (2)

Sandwich (2)

Target

HTRA2 / OMI (4)

Reactivity

Human (2)

Mouse (1)

Bovine (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (3)

Publications

No (4)

Sample Type

Cell Culture Supernatants (1)

Plasma (2)

Serum (2)

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Human HTRA2 / OMI (Sandwich ELISA) ELISA Kit - LS-F101

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.205 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$840

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Human HTRA2 / OMI (Sandwich ELISA) ELISA Kit - LS-F49630

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Bovine HTRA2 / OMI (Custom ELISA) ELISA Kit - LS-F49519

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse HTRA2 / OMI (Custom ELISA) ELISA Kit - LS-F49520

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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