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The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: | 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic |
Synonyms: | HTR3D, 5-HT3D, 5HT3D, 5-HT3-D, Serotonin 5-HT-3D receptor, Serotonin receptor 3D |
Target Sequences: | Q70Z44 Q70Z44 |
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