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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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HTR2C / 5-HT2C Receptor

5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR2C, 5-HT-1C, 5-HT1c receptor, 5HT-1C, 5-HT2C, 5-HT2c receptor, 5HT2C Receptor, 5-HT-2C, 5-HT1C, 5-HTR2C, HTR1C, Serotonin 5-HT-1c receptor, Serotonin receptor 2C, Serotonin 1c receptor, Serotonin 5-HT-2C receptor, Serotonin 2c receptor
Target Sequences: nm_000868 NP_000859.1 P28335

Publications (1)

1
Human polyomavirus receptor distribution in brain parenchyma contrasts with receptor distribution in kidney and choroid plexus. Haley SA, O'Hara BA, Nelson CD, Brittingham FL, Henriksen KJ, Stopa EG, Atwood WJ. The American journal of pathology. 2015 August;185:2246-58. (Human) [Full Text Article] [PubMed:26056932] [PMC:PMC4530127] Related Antibodies: LS-A1119.

Viewing 1-25 of 56 items
HTR2C / 5-HT2C Receptor Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
50µl   $425.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human pancreas, ganglion and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human uterus, glandular cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
HTR2C / 5-HT2C Receptor Antibody - Anti-5HT2C Receptor antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal to Human HTR2C / 5-HT2C Receptor
Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
HTR2C / 5-HT2C Receptor Antibody - Western blot of SR-2C antibody
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Rabbit Polyclonal (IgG) to Human HTR2C / 5-HT2C Receptor
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
HTR2C / 5-HT2C Receptor Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using 5-HT-2C Antibody. The picture on the right is blocked with the synthesized peptide.
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Rabbit Polyclonal (IgG) to Human HTR2C / 5-HT2C Receptor
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00

Viewing 1-25 of 56 items


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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).