HTR2A / 5-HT2A Receptor

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

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Products

ELISA Kits (8)

Type

Custom (3)

Sandwich (5)

Target

HTR2A / 5-HT2A Receptor (8)

Reactivity

Human (2)

Mouse (1)

Rat (2)

Bovine (1)

Dog (1)

Pig (1)

Format

96-Well Strip Plate (8)

Publications

No (8)

Sample Type

Cell Lysates (1)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

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Human HTR2A / 5-HT2A Receptor (Sandwich ELISA) ELISA Kit - LS-F8839

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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Human HTR2A / 5-HT2A Receptor (Sandwich ELISA) ELISA Kit - LS-F66913

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse HTR2A / 5-HT2A Receptor (Sandwich ELISA) ELISA Kit - LS-F66744

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat HTR2A / 5-HT2A Receptor (Sandwich ELISA) ELISA Kit - LS-F53625

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$1,041

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Bovine HTR2A / 5-HT2A Receptor (Custom) ELISA Kit - LS-F65381

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$783

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Pig HTR2A / 5-HT2A Receptor (Custom) ELISA Kit - LS-F65435

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Price:

1 Plate/$783

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Dog HTR2A / 5-HT2A Receptor (Custom) ELISA Kit - LS-F66005

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Price:

1 Plate/$929

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Rat HTR2A / 5-HT2A Receptor (Sandwich ELISA) ELISA Kit - LS-F66818

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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