G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
|Gene Name:||5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled|
|Family/Subfamily:||GPCR , Serotonin|
|Synonyms:||HTR1F, 5-HT1F, 5-HT1f receptor, 5HT1F Receptor, 5-HT-1F, 5HT6, HTR1EL, MR77, Serotonin 1f receptor, Serotonin 5-HT-1f receptor, Serotonin receptor 1F|
|Target Sequences:||NM_000866 NP_000857.1 P30939|
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