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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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LSBio
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Seattle WA 98121
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866-819-4732 (Toll Free North America
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HTR1B / 5-HT1B Receptor

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1b receptor, 5-HT1DB, 5HT1B Receptor, HTR1DB, Serotonin 5-HT-1b receptor, Serotonin receptor 1B, Serotonin 1b receptor, HTR1D2, Serotonin 1D beta receptor
Target Sequences: NM_000863 NP_000854.1 P28222


HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Human Liver, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
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Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
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Mouse Monoclonal (IgG1) to Human HTR1B / 5-HT1B Receptor
Human
IHC
Unconjugated
100µg   $650.00
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
HTR1B / 5-HT1B Receptor Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Human
WB
Unconjugated
100µl   0.5mg/ml   $325.00
HTR1B / 5-HT1B Receptor Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100µl   1mg/ml   $335.00
HTR1B / 5-HT1B Receptor Antibody - Western blot of 5-HT1BR in human brain lysate with anti-5-HT1BR pcAb. A protein band of approximate molecular weight of 40-41kD was detected.
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Rabbit Polyclonal (IgG) to Rat HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
WB
Unconjugated
100µg   200µl   0.5mg/ml   $335.00
HTR1B / 5-HT1B Receptor Antibody - Antibody (2 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Goat Polyclonal to Human HTR1B / 5-HT1B Receptor
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
HTR1B / 5-HT1B Receptor Antibody - Immunofluorescence analysis of A549 cells, using HTR1B Antibody. The picture on the right is blocked with the synthesized peptide.
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
HTR1B / 5-HT1B Receptor Antibody - Western blot analysis of the lysates from HepG2 cells using 5-HT-1B antibody.
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
HTR1B / 5-HT1B Receptor Antibody - Western blot analysis of the lysates from COLO205 cells using HTR1B antibody.
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
HTR1B / 5-HT1B Receptor Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).