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HTR1B / 5-HT1B Receptor

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1b receptor, 5-HT1DB, 5HT1B Receptor, HTR1DB, Serotonin 5-HT-1b receptor, Serotonin receptor 1B, Serotonin 1b receptor, HTR1D2, Serotonin 1D beta receptor
Target Sequences: NM_000863 NP_000854.1 P28222

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Products
Antibodies (26)
Primary (26)
HTR1B / 5-HT1B Receptor (26)
Human (25)
Mouse (12)
Rat (12)
Bat (2)
Bovine (2)
Chicken (1)
Chimpanzee (3)
Dog (2)
Gibbon (3)
Guinea pig (2)
Hamster (2)
Horse (1)
Monkey (2)
Pig (1)
Rabbit (2)
Xenopus (1)
IHC (6)
IHC-P (3)
WB (21)
ELISA (8)
IF (6)
Peptide-ELISA (7)
rabbit (24)
mouse (1)
goat (1)
Product Group
GPCR Database Antibodies (3)
IHCPlus (1)
PathPlus Cancer (2)
IgG (20)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (25)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
aa225-253 (7)
N-Terminus (4)
aa8-26 (2)
180-260 aa, Internal (1)
Cytoplasmic Domain (1)
Internal (1)
aa179-228 (1)
aa201-250 (1)
aa256-305 (1)
aa261-310 (1)
aa372-382 (1)
No (26)
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
HTR1B / 5-HT1B Receptor Antibody - Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
Unconjugated
50 µg/$460
HTR1B / 5-HT1B Receptor Antibody - Antibody (2 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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HTR1B / 5-HT1B Receptor Goat anti-Human Polyclonal (aa372-382) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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HTR1B / 5-HT1B Receptor Mouse anti-Human Monoclonal Antibody
Human
IHC
Unconjugated
100 µg/$872
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HTR1B / 5-HT1B Receptor Antibody - Western blot analysis of the lysates from HepG2 cells using 5-HT-1B antibody.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa179-228) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HTR1B / 5-HT1B Receptor Antibody - Western blot of 5-HT1BR in human brain lysate with anti-5-HT1BR pcAb. A protein band of approximate molecular weight of 40-41kD was detected.
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HTR1B / 5-HT1B Receptor Rabbit anti-Rat Polyclonal (aa8-26) Antibody
Mouse, Rat, Human
WB
Unconjugated
0.1 mg/$386
HTR1B / 5-HT1B Receptor Antibody - Human Liver, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
HTR1B / 5-HT1B Receptor Antibody - Immunofluorescence analysis of A549 cells, using HTR1B Antibody. The picture on the right is blocked with the synthesized peptide.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa261-310) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HTR1B / 5-HT1B Receptor Antibody - Western blot analysis of the lysates from COLO205 cells using HTR1B antibody.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa256-305) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HTR1B / 5-HT1B Receptor Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
HTR1B / 5-HT1B Receptor Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$442
HTR1B / 5-HT1B Receptor Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$442
HTR1B / 5-HT1B Receptor Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HTR1B / 5-HT1B Receptor Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using 5-HT-1B Antibody. The picture on the right is blocked with the synthesized peptide.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
HTR1B / 5-HT1B Receptor Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using HTR1B antibody.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
HTR1B / 5-HT1B Receptor Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
HTR1B / 5-HT1B Receptor Antibody - HTR1B Antibody western blot of HL-60 cell line lysates (35 ug/lane). The HTR1B antibody detected the HTR1B protein (arrow).
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HTR1B / 5-HT1B Receptor Rabbit anti-Human Polyclonal (aa225-253) Antibody
Human
WB
Unconjugated
400 µl/$393
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HTR1B / 5-HT1B Receptor Rabbit anti-Rat Polyclonal (aa8-26) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$649
Viewing 1-25 of 26 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).