HSPG2 / Perlecan

heparan sulfate proteoglycan 2

Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.Endorepellin in an anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6.The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

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Products

ELISA Kits (10)

Type

Custom (1)

Sandwich (8)

Sandwich CLIA (1)

Target

HSPG2 / Perlecan (10)

Reactivity

Human (7)

Mouse (3)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (8)

Publications

No (10)

Sample Type

Cell Culture Supernatants (1)

Citrate Plasma (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (8)

Serum (9)

Tissue Homogenates (4)

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F6348

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F57116

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.624 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$1,150

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Mouse HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F7064

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F13386

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human HSPG2 / Perlecan (CLIA) ELISA Kit - LS-F29375

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F35413

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F35415

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F52061

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$958

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Human HSPG2 / Perlecan (Custom ELISA) ELISA Kit - LS-F50226

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

Select

Mouse HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F12314

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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