HSPG2 / Perlecan

heparan sulfate proteoglycan 2

Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.Endorepellin in an anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6.The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

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Products

Antibodies (37)

ELISA Kits (10)

Proteins (3)

Type

Custom (1)

Over-Expression Lysate (1)

Primary (37)

Recombinant (2)

Sandwich (8)

Sandwich CLIA (1)

Target

HSPG2 / Perlecan (50)

Reactivity

Human (44)

Mouse (19)

Rat (10)

Bovine (9)

Monkey (5)

Pig (13)

Application

IHC (17)

IHC-Fr (5)

IHC-P (8)

WB (31)

Flo (5)

ELISA (11)

ICC (11)

IF (5)

IP (12)

Peptide-ELISA (1)

Host

rabbit (12)

mouse (19)

rat (6)

Product Group

IHCPlus (2)

Isotype

IgG (13)

IgG1 (7)

IgG1,k (2)

IgG2a (1)

IgG2a,k (5)

Clonality

monoclonal mc (25)

polyclonal pc (12)

Clone

A71 (1)

A74 (1)

A7L6 (4)

SPM255 (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (8)

APC (2)

APC Conjugated (3)

Azide-free (2)

Biotin Conjugated (4)

BSA-free (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (3)

PE Conjugated (3)

Ready-to-Use (1)

Unconjugated (16)

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Epitope

aa4149-4391 (18)

Domain V (1)

aa524-701 (1)

Publications

No (49)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Citrate Plasma (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (8)

Serum (9)

Tissue Homogenates (4)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (1)

Species

Human (2)

Source

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ HSPG2 / Perlecan Antibody (clone A7L6) LS-B10057

(4.0) Rating

Antibody:

HSPG2 / Perlecan Rat anti-Human Monoclonal (A7L6) Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

ICC, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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IHC-plus™ HSPG2 / Perlecan Antibody (clone A71) LS-B2468

(4.0) Rating

Antibody:

HSPG2 / Perlecan Mouse anti-Bovine Monoclonal (A71) Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$585

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HSPG2 / Perlecan Antibody LS-C15763

Antibody:

HSPG2 / Perlecan Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$786

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HSPG2 / Perlecan Antibody (HRP) LS-C546607

Antibody:

HSPG2 / Perlecan Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

100 µl/$1,017

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HSPG2 / Perlecan Antibody (Biotin) LS-C526500

Antibody:

HSPG2 / Perlecan Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,017

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HSPG2 / Perlecan Antibody (APC) LS-C517134

Antibody:

HSPG2 / Perlecan Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

100 µl/$1,017

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HSPG2 / Perlecan Antibody (PE) LS-C654669

Antibody:

HSPG2 / Perlecan Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

100 µl/$1,017

• Unconjugated
• HRP
• Biotin
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • APC
  • PE

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F6348

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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HSPG2 / Perlecan Antibody (clone A7L6) LS-C390348

(4.0) Rating

(1) Publication(s)

Antibody:

HSPG2 / Perlecan Rat anti-Mouse Monoclonal (A7L6) Antibody

Reactivity:

Mouse, Bovine, Pig, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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HSPG2 / Perlecan Antibody (clone A7L6, Ready-to-Use) LS-C390352

Antibody:

HSPG2 / Perlecan Rat anti-Mouse Monoclonal (Ready-to-Use) (A7L6) Antibody

Reactivity:

Mouse, Bovine, Pig, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

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HSPG2 / Perlecan Antibody (clone A7L6, Azide-free, BSA-free) LS-C390353

Antibody:

HSPG2 / Perlecan Rat anti-Mouse Monoclonal (Azide-free, BSA-free) (A7L6) Antibody

Reactivity:

Mouse, Bovine, Pig, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Ready-to-Use
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Ready-to-Use
• Unconjugated, Azide-free, BSA-free

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HSPG2 / Perlecan Antibody (clone SPM255) LS-C390351

Antibody:

HSPG2 / Perlecan Rat anti-Mouse Monoclonal (SPM255) Antibody

Reactivity:

Mouse, Bovine, Pig, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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HSPG2 / Perlecan Antibody (clone SPM255, Azide-free, BSA-free) LS-C390350

Antibody:

HSPG2 / Perlecan Rat anti-Mouse Monoclonal (Azide-free, BSA-free) (SPM255) Antibody

Reactivity:

Mouse, Bovine, Pig, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Azide-free, BSA-free

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HSPG2 / Perlecan Antibody (Domain V, clone A74) LS-C15758

Antibody:

HSPG2 / Perlecan Mouse anti-Bovine Monoclonal (Domain V) (A74) Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

100 µl/$1,146

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F57116

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.624 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$1,150

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Mouse HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F7064

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

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HSPG2 / Perlecan Antibody LS-C15759

Antibody:

HSPG2 / Perlecan Mouse anti-Bovine Monoclonal Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

100 µl/$1,146

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HSPG2 / Perlecan Antibody (aa524-701) LS-C357466

Antibody:

HSPG2 / Perlecan Rabbit anti-Human Polyclonal (aa524-701) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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HSPG2 / Perlecan Antibody (aa4149-4391) LS-C314290

Antibody:

HSPG2 / Perlecan Mouse anti-Human Monoclonal (aa4149-4391) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296

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HSPG2 / Perlecan Antibody (aa4149-4391) LS-C294461

Antibody:

HSPG2 / Perlecan Rabbit anti-Human Polyclonal (aa4149-4391) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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HSPG2 / Perlecan Antibody (aa4149-4391, FITC) LS-C694250

Antibody:

HSPG2 / Perlecan Rabbit anti-Human Polyclonal (aa4149-4391) (FITC) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

• Unconjugated
• FITC

• Unconjugated
• FITC

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Human HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F13386

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human HSPG2 / Perlecan Protein (Recombinant His, N-Terminal) (Leu4149-Ser4391) - LS-G15034

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

27.0 kDa

Price:

10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934

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Human HSPG2 / Perlecan (CLIA) ELISA Kit - LS-F29375

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse HSPG2 / Perlecan (Sandwich ELISA) ELISA Kit - LS-F35413

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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