order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
HSPB8 / H11 / HSP22
heat shock 22kDa protein 8
HSPB8 / H11 / HSP22 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
| Gene Name: | heat shock 22kDa protein 8 |
| Family/Subfamily: | Protein Kinase , H11 |
| Synonyms: | HSPB8, Alpha-crystallin C chain, CMT2L, Crystallin alpha c, DHMN2, E2-induced gene 1 protein, CRYAC, E2IG1, HMN2, H11, Heat shock 27kDa protein 8, Heat shock protein beta-8, Heat shock 22kDa protein 8, HMN2A, HSP22, Protein kinase H11 |
| Target Sequences: | NM_014365 NP_055180.1 Q9UJY1 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
