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Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Gene Name: | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
Synonyms: | HSP90AB1, D6S182, Heat shock 84 kDa, Heat shock protein beta, Heat shock protein HSP 90-beta, HSP 84, HSP84, HSP 90, HSP90-BETA, HSP90B, HSPC2, HSPCB |
Target Sequences: | NM_007355 NP_031381.2 P08238 |
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